Barrios, Roberto

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selected publications

Cardiac Afferent Denervation Abolishes Ganglionated Plexi and Sympathetic Responses to Apnea: Implications for Atrial Fibrillation. Circulation. Arrhythmia and electrophysiology. 2020 Academic Article GET IT
Times cited: 19
Retraction: Inactivation of the Quinone Oxidoreductases NQO1 and NQO2 Strongly Elevates the Incidence and Multiplicity of Chemically Induced Skin Tumors. Cancer research. 2018 Academic Article GET IT
Times cited: 2
Retraction: NRH:Quinone Oxidoreductase 2-Deficient Mice Are Highly Susceptible to Radiation-induced B-Cell Lymphomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 Academic Article GET IT
Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice. American journal of physiology. Lung cellular and molecular physiology. 2018 Academic Article GET IT
Times cited: 31
Hyperoxia Disrupts Extracellular Signal-Regulated Kinases 1/2-Induced Angiogenesis in the Developing Lungs. International journal of molecular sciences. 2018 Academic Article GET IT
Times cited: 12
Long-term pulmonary and cardiovascular morbidities of neonatal hyperoxia exposure in mice. The international journal of biochemistry & cell biology. 2017 Academic Article GET IT
Programmed Death Ligand-1 (PD-L1) Expression in Either Tumor Cells or Tumor-Infiltrating Immune Cells Correlates With Solid and High-Grade Lung Adenocarcinomas. Archives of pathology & laboratory medicine. 2017 Academic Article GET IT
Times cited: 13
Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal β-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants. Toxicological sciences : an official journal of the Society of Toxicology. 2017 Academic Article GET IT
Times cited: 25
Involvement of the Bufadienolides in the Detection and Therapy of the Acute Respiratory Distress Syndrome. Lung. 2017 Academic Article GET IT
Diagnosis of Acute Cellular Rejection and Antibody-Mediated Rejection on Lung Transplant Biopsies: A Perspective From Members of the Pulmonary Pathology Society. Archives of pathology & laboratory medicine. 2016 Academic Article GET IT
Times cited: 22
Phenotypic assessment of pulmonary hypertension using high-resolution echocardiography is feasible in neonatal mice with experimental bronchopulmonary dysplasia and pulmonary hypertension: a step toward preventing chronic obstructive pulmonary disease. International journal of chronic obstructive pulmonary disease. 2016 Academic Article GET IT
Times cited: 24
Impact of Recent Developments in Lung Cancer on the Practice of Pathology. Archives of pathology & laboratory medicine. 2016 Review GET IT
Times cited: 5
Folate Receptor α Expression Level Correlates With Histologic Grade in Lung Adenocarcinoma. Archives of pathology & laboratory medicine. 2015 Academic Article GET IT
Times cited: 13
Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury. Free radical biology & medicine. 2015 Academic Article GET IT
Times cited: 29
Magnetically guided recellularization of decellularized stented porcine pericardium-derived aortic valve for TAVI. ASAIO journal (American Society for Artificial Internal Organs : 1992). 2014 Academic Article GET IT
Times cited: 9
Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress. Toxicological sciences : an official journal of the Society of Toxicology. 2014 Academic Article GET IT
Times cited: 44
Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene. Toxicology letters. 2014 Academic Article GET IT
Times cited: 23
High proportion of patients with end-stage heart failure regardless of aetiology demonstrates anti-cardiac antibody deposition in failing myocardium: humoral activation, a potential contributor of disease progression. European heart journal. 2013 Academic Article GET IT
Times cited: 23
The presence of anti-HLA donor-specific antibodies in lung allograft recipients does not correlate with C4d immunofluorescence in transbronchial biopsy specimens. Archives of pathology & laboratory medicine. 2013 Academic Article GET IT
Times cited: 13
Sex-specific differences in hyperoxic lung injury in mice: implications for acute and chronic lung disease in humans. Toxicology and applied pharmacology. 2013 Academic Article GET IT
Times cited: 42
Portal application of human unrestricted somatic stem cells to support hepatic regeneration after portal embolization and tumor surgery. ASAIO journal (American Society for Artificial Internal Organs : 1992). 2012 Academic Article GET IT
Times cited: 9
Rapidly progressive, fatal, inhalation anthrax-like infection in a human: case report, pathogen genome sequencing, pathology, and coordinated response. 2011 GET IT
Times cited: 38
Prenatal administration of the cytochrome P4501A inducer, Β-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants. Toxicology and applied pharmacology. 2011 Academic Article GET IT
Times cited: 41
Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo. Biochemical and biophysical research communications. 2011 Academic Article GET IT
Times cited: 9
Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors. Cancer research. 2010 Academic Article GET IT
Times cited: 46
NRH:quinone oxidoreductase 2-deficient mice are highly susceptible to radiation-induced B-cell lymphomas. Clinical cancer research : an official journal of the American Association for Cancer Research. 2009 Academic Article GET IT
Times cited: 11
Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to radiation-induced myeloproliferative disease. Cancer research. 2008 Academic Article GET IT
Times cited: 26
Enforced epithelial expression of IGF-1 causes hyperplastic prostate growth while negative selection is requisite for spontaneous metastogenesis. Oncogene. 2007 Academic Article GET IT
Times cited: 23
In vivo role of NAD(P)H:quinone oxidoreductase 1 in metabolic activation of mitomycin C and bone marrow cytotoxicity. Cancer research. 2007 Academic Article GET IT
Times cited: 12
Acute antibody-mediated rejection of renal transplant: pathogenetic and diagnostic considerations. Archives of pathology & laboratory medicine. 2007 Information Resource GET IT
Times cited: 15
MUC4 expression in non-small cell lung carcinomas: relationship to tumor histology and patient survival. Archives of pathology & laboratory medicine. 2007 Academic Article GET IT
Times cited: 39
Expression of glutathione S-transferase pi and glutathione synthase correlates with survival in early stage non-small cell carcinomas of the lung. Human pathology. 2007 Academic Article GET IT
Times cited: 22
In vivo plaque characterization using intravascular ultrasound-virtual histology in a porcine model of complex coronary lesions. Arteriosclerosis, thrombosis, and vascular biology. 2006 Academic Article GET IT
Times cited: 91
Pleuropulmonary desmoid tumors: immunohistochemical comparison with solitary fibrous tumors and assessment of beta-catenin and cyclin D1 expression. Archives of pathology & laboratory medicine. 2006 Academic Article GET IT
Times cited: 33
Expression of renal cell carcinoma-associated markers erythropoietin, CD10, and renal cell carcinoma marker in diffuse malignant mesothelioma and metastatic renal cell carcinoma. Archives of pathology & laboratory medicine. 2006 Academic Article GET IT
Times cited: 41
Asthma: pathology and pathophysiology. Archives of pathology & laboratory medicine. 2006 Information Resource GET IT
Times cited: 66
Modulation of pulmonary cytochrome P4501A1 expression by hyperoxia and inhaled nitric oxide in the newborn rat: implications for lung injury. Pediatric research. 2006 Academic Article GET IT
Times cited: 11
Attenuation of oxygen-induced abnormal lung maturation in rats by retinoic acid: possible role of cytochrome P4501A enzymes. The Journal of pharmacology and experimental therapeutics. 2006 Academic Article GET IT
Times cited: 23
BALT development and augmentation of hyperoxic lung injury in mice deficient in NQO1 and NQO2. Free radical biology & medicine. 2006 Academic Article GET IT
Times cited: 28
Effects of 3-methylcholanthrene on gene expression profiling in the rat using cDNA microarray analyses. Chemical research in toxicology. 2005 Academic Article GET IT
Times cited: 29
Attenuation of hyperoxic lung injury by the CYP1A inducer beta-naphthoflavone. Toxicological sciences : an official journal of the Society of Toxicology. 2005 Academic Article GET IT
Times cited: 34
Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis. Cancer research. 2005 Academic Article GET IT
Times cited: 71
Retinoic acid slows progression and promotes apoptosis of spontaneous prostate cancer. The Prostate. 2004 Academic Article GET IT
Times cited: 43
Conditional deletion of Rb causes early stage prostate cancer. Cancer research. 2004 Academic Article GET IT
Times cited: 84
Post-transplant nephrotic syndrome: A comprehensive clinicopathologic study. Kidney international. 2004 Academic Article GET IT
Times cited: 49
Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury. The Journal of pharmacology and experimental therapeutics. 2004 Academic Article GET IT
Times cited: 58
Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee. Cancer research. 2004 Conference Paper GET IT
Times cited: 442
Differential expression of cell cycle regulatory molecules and evidence for a "cyclin switch" during progression of prostate cancer. The Prostate. 2004 Academic Article GET IT
Times cited: 38
Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice. Endocrinology. 2003 Academic Article GET IT
Times cited: 45
SU5416 selectively impairs angiogenesis to induce prostate cancer-specific apoptosis. Molecular cancer therapeutics. 2003 Academic Article GET IT
Times cited: 40
Pathobiology of autochthonous prostate cancer in a pre-clinical transgenic mouse model. The Prostate. 2003 Academic Article GET IT
Times cited: 352
Light chain crystal deposition as a manifestation of plasma cell dyscrasias: the role of immunoelectron microscopy. Human pathology. 2003 Academic Article GET IT
Times cited: 36
Differential expression of specific FGF ligand and receptor isoforms during angiogenesis associated with prostate cancer progression. The Prostate. 2003 Academic Article GET IT
Times cited: 49
Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels. Stroke. 2003 Academic Article GET IT
Times cited: 49
Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice. American journal of respiratory and critical care medicine. 2002 Academic Article GET IT
Times cited: 53
Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity. The Journal of biological chemistry. 2002 Academic Article GET IT
Times cited: 98
Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo. The American journal of pathology. 2002 Academic Article GET IT
Times cited: 51
Gamma-glutamyl transpeptidase-deficient mice are resistant to the nephrotoxic effects of cisplatin. The American journal of pathology. 2001 Academic Article GET IT
Times cited: 94
Nonlupus nephritides in patients with systemic lupus erythematosus: a comprehensive clinicopathologic study and review of the literature. Human pathology. 2001 Academic Article GET IT
Angiogenesis and prostate cancer: identification of a molecular progression switch. Cancer research. 2001 Academic Article GET IT
Times cited: 205
Oxygen-induced pulmonary injury in gamma-glutamyl transpeptidase-deficient mice. Lung. 2001 Academic Article GET IT
Times cited: 44
TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?. American journal of physiology. Lung cellular and molecular physiology. 2000 Academic Article GET IT
Times cited: 331
Genomic instability-based transgenic models of prostate cancer. Carcinogenesis. 2000 Academic Article GET IT
Times cited: 25
Glutathione synthesis is essential for mouse development but not for cell growth in culture. Proceedings of the National Academy of Sciences of the United States of America. 2000 Academic Article GET IT
Times cited: 257
Increase of lung neutrophils in hypersensitivity pneumonitis is associated with lung fibrosis. American journal of respiratory and critical care medicine. 2000 Academic Article GET IT
Times cited: 111
E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse. Cancer research. 2000 Academic Article GET IT
Times cited: 151
Response from lieberman and colleagues. Environmental health perspectives. 1999 Academic Article GET IT
Mouse leukotriene A4 hydrolase is expressed at high levels in intestinal crypt cells and splenic lymphocytes. Gene. 1999 Academic Article GET IT
Times cited: 9
Therapeutic efficacy of an anti-IL-5 monoclonal antibody delivered into the respiratory tract in a murine model of asthma. The Journal of allergy and clinical immunology. 1999 Academic Article GET IT
Times cited: 57
Pathologic progression of autochthonous prostate cancer in the TRAMP model. Prostate cancer and prostatic diseases. 1999 Academic Article GET IT
Cyclosiloxanes produce fatal liver and lung damage in mice. Environmental health perspectives. 1999 Academic Article GET IT
Times cited: 71
gamma-glutamyl leukotrienase, a gamma-glutamyl transpeptidase gene family member, is expressed primarily in spleen. The Journal of biological chemistry. 1998 Academic Article GET IT
Times cited: 46
Gelatinases A and B are up-regulated in rat lungs by subacute hyperoxia: pathogenetic implications. The American journal of pathology. 1998 Academic Article GET IT
Times cited: 106
Impaired adaptive vascular growth in hypercholesterolemic rabbit. Atherosclerosis. 1998 Academic Article GET IT
Times cited: 14
Local inflammatory response and vector spread after direct intraprostatic injection of a recombinant adenovirus containing the herpes simplex virus thymidine kinase gene and ganciclovir therapy in mice. Cancer gene therapy. 1998 Academic Article GET IT
Times cited: 54
Androgen-independent prostate cancer progression in the TRAMP model. Cancer research. 1997 Academic Article GET IT
Times cited: 285
Upregulation of acidic fibroblast growth factor during development of experimental lung fibrosis. The American journal of physiology. 1997 Academic Article GET IT
Times cited: 36
Four distinct membrane bound dipeptidase rnas are differentially expressed in the mouse. FASEB Journal. 1996 Article
Immunohistochemistry and molecular biology markers of renal transplant rejection: Diagnostic applications. Transplantation Reviews. 1996 Article
Tobacco smoke-induced lung emphysema in guinea pigs is associated with increased interstitial collagenase. The American journal of physiology. 1996 Academic Article GET IT
Times cited: 71
Increased expression of gelatinases and collagenase in rat lungs exposed to 100% oxygen. American journal of respiratory and critical care medicine. 1996 Academic Article GET IT
Times cited: 77
Metastatic prostate cancer in a transgenic mouse. Cancer research. 1996 Academic Article GET IT
Times cited: 476
Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 1996 Academic Article GET IT
Times cited: 332
Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase. The Journal of biological chemistry. 1996 Academic Article GET IT
Times cited: 27
Retention of p53val135 wild-type function in transgenic mice. Laboratory investigation; a journal of technical methods and pathology. 1996 Academic Article GET IT
Times cited: 4
RasT24 driven by a probasin promoter induces prostatic hyperplasia in transgenic mice. Transgenics. 1996 Article
Tenascin is an ubiquitous extracellular matrix protein of human renal interstitium in normal and pathologic conditions. Nephron. 1996 Academic Article GET IT
Times cited: 27
gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?. The American journal of pathology. 1995 Information Resource GET IT
Times cited: 123
Renal neoplasm in acquired cystic kidney disease. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1995 Information Resource GET IT
Times cited: 94
Transgenic mice carrying a PSArasT24 hybrid gene develop salivary gland and gastrointestinal tract neoplasms. Laboratory investigation; a journal of technical methods and pathology. 1995 Academic Article GET IT
Times cited: 29
Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine. The Journal of biological chemistry. 1994 Academic Article GET IT
Times cited: 13
The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice. Molecular endocrinology (Baltimore, Md.). 1994 Academic Article GET IT
Times cited: 237
Tenascin is an important component of the glomerular extracellular matrix in normal and pathologic conditions. Kidney international. 1994 Academic Article GET IT
Times cited: 58
Expression of the rasT24 oncogene in the ciliary body pigment epithelium and retinal pigment epithelium results in hyperplasia, adenoma, and adenocarcinoma. The American journal of pathology. 1993 Academic Article GET IT
Times cited: 8
Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys. The American journal of pathology. 1993 Academic Article GET IT
Times cited: 81
Pulmonary arterial hypertension and cor pulmonale associated with chronic domestic woodsmoke inhalation. Chest. 1993 Academic Article GET IT
Times cited: 99
[Analysis of rheumatic valvulopathy with scanning electron microscopy]. Archivos del Instituto de Cardiologia de Mexico. 1992 Academic Article GET IT
Effect of hydralazine on vascular mechanics in a canine lobar preparation of pulmonary embolism. Lung. 1992 Academic Article GET IT
Times cited: 5
Entamoeba histolytica: microtubule movement during mitosis. Experimental parasitology. 1991 Academic Article GET IT
Times cited: 17
[The effect of gelfoam embolism in vascular conduction and critical pressure in the isolated canine lobe]. Archivos del Instituto de Cardiologia de Mexico. 1990 Academic Article GET IT
Mast cells and idiopathic lung fibrosis. Archivos de investigacion medica. 1990 Academic Article GET IT
Times cited: 9
Infection kinetics of the macrophage J774.2 cell-line with Histoplasma capsulatum. Revista Latinoamericana de Microbiologia. 1989 Article
Experimental pulmonary fibrosis induced by paraquat plus oxygen in rats: a morphologic and biochemical sequential study. Experimental and molecular pathology. 1989 Academic Article GET IT
Times cited: 21
[Pulmonary blood volume in patients with interstitial pneumopathy and pulmonary heart disease. Its study at rest and during exercise]. Archivos del Instituto de Cardiologia de Mexico. 1988 Academic Article GET IT
Comparison of transbronchial and open lung biopsies in interstitial lung diseases. Archivos de investigacion medica. 1988 Academic Article GET IT
Times cited: 2
Prevalence and severity of coronary atherosclerosis in males living in Mexico City: the Mexico City project. Cardiology. 1988 Academic Article GET IT
Times cited: 7
Subpopulations of T cells in lung biopsies from patients with pigeon breeder's disease. Lung. 1987 Academic Article GET IT
Times cited: 13
Mechanism of glomerular permeability reduction in nonclipped kidney of rats with goldblatt hypertension. Hypertension. 1986 Article
Pigeon breeder's disease: immunofluorescence and ultrastructural observations. Lung. 1986 Academic Article GET IT
Times cited: 9
[A change in glomerular permeability in renovascular hypertension. Participation of angiotensin and structural lesions]. Archivos del Instituto de Cardiologia de Mexico. 1986 Academic Article GET IT
Hemodynamic effect of hydralazine in interstitial lung disease patients with cor pulmonale. Immediate and short-term evaluation at rest and during exercise. Chest. 1985 Academic Article GET IT
Follicular bronchiolitis in association with connective tissue diseases. Lung. 1985 Academic Article GET IT
Times cited: 74
[Ciliary changes in interstitial pneumonia]. Gaceta medica de Mexico. 1985 Academic Article GET IT
[Reticulovascular radiologic pattern in primary arterial pulmonary hypertension]. Archivos del Instituto de Cardiologia de Mexico. 1984 Academic Article GET IT
Peripheral airways obstruction in idiopathic pulmonary artery hypertension (primary). Chest. 1983 Academic Article GET IT
Times cited: 34
Hypersensitivity pneumonitis in man. Light- and electron-microscopic studies of 18 lung biopsies. The American journal of pathology. 1983 Academic Article GET IT
Times cited: 130
[Respiratory function in extrinsic allergic alveolitis caused by pigeons. Clinical, pathological and functional correlation]. Archivos del Instituto de Cardiologia de Mexico. 1982 Academic Article GET IT
Times cited: 2
Extrinsic allergic alveolitis caused by pigeon breeding at a high altitude (2,240 meters). Hemodynamic behavior of pulmonary circulation. The American review of respiratory disease. 1981 Academic Article GET IT
Times cited: 24
Familial pigeon breeder's disease. Possible association to HLA-Bw40 antigen. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion. 1980 Academic Article GET IT
Times cited: 2
Zymosan-induced experimental hypersensitivity pneumonitis in rabbits. The American journal of pathology. 1980 Academic Article GET IT
Times cited: 8
[Pulmonary eosinophilia and pulmonary arterial hypertension]. Archivos del Instituto de Cardiologia de Mexico. 1979 Academic Article GET IT
[Recent advances of knowledge about pulmonary edema]. Archivos del Instituto de Cardiologia de Mexico. 1978 Editorial Article GET IT
[Comparative study of the pulmonary and bronchial circulations. I. Intercellular junctions]. Archivos del Instituto de Cardiologia de Mexico. 1978 Academic Article GET IT
[Ultrastructural observations on experimental shock lung]. Archivos del Instituto de Cardiologia de Mexico. 1978 Academic Article GET IT
Times cited: 1
Intercellular junctions in "shock lung". A freeze-fracture study. Laboratory investigation; a journal of technical methods and pathology. 1977 Academic Article GET IT
Times cited: 7
Gram-negative pneumonias in surgical patients. Complication of antibiotic treatment. Archives of surgery (Chicago, Ill. : 1960). 1973 Academic Article GET IT
Times cited: 2

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Background

education and training

M.D., National Autonomous University of Mexico, Faculty of Medicine (Mexico) 1969
B.S., University Centro Mexico (Mexico) 1962

Contact

full name

Roberto Barrios

VIVO Weill Cornell Medical College

Roberto Barrios Professor of Pathology and Laboratory Medicine

Publications

selected publications

Background

education and training

Contact

full name