Yaeger, Rona

selected publications

EGFR Blockade Reverts Resistance to KRAS^G12C Inhibition in Colorectal Cancer. Cancer discovery. 2020 Academic Article GET IT
Times cited: 283
Systemic Chemotherapy for Metastatic Colitis-Associated Cancer Has a Worse Outcome Than Sporadic Colorectal Cancer: Matched Case Cohort Analysis. Clinical colorectal cancer. 2020 Academic Article GET IT
Times cited: 1
A rectal cancer organoid platform to study individual responses to chemoradiation. Nature medicine. 2019 Academic Article GET IT
Times cited: 345
Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy. JAMA oncology. 2019 Academic Article GET IT
Times cited: 408
Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions. Cancer research. 2019 Academic Article GET IT
Times cited: 115
RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling. Nature medicine. 2018 Academic Article GET IT
Times cited: 134
Microsatellite Instability Is Associated With the Presence of Lynch Syndrome Pan-Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2018 Academic Article GET IT
Times cited: 420
Association of Preoperative and Postoperative Serum Carcinoembryonic Antigen and Colon Cancer Outcome. JAMA oncology. 2018 Academic Article GET IT
Times cited: 164
Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAF^V600E-Mutant Colorectal Cancer. Cancer discovery. 2018 Academic Article GET IT
Times cited: 436
Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer. Cancer cell. 2018 Academic Article GET IT
Times cited: 574
Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition. Cancer research. 2017 Academic Article GET IT
Times cited: 67
Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. 2017 GET IT
Times cited: 23
Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS. Nature. 2017 Academic Article GET IT
Times cited: 402
Clinical and Morphologic Characteristics of MEK Inhibitor-Associated Retinopathy: Differences from Central Serous Chorioretinopathy. Ophthalmology. 2017 Academic Article GET IT
Times cited: 102
OncoKB: A Precision Oncology Knowledge Base. JCO precision oncology. 2017 Academic Article GET IT
Times cited: 1720
PI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases. Oncotarget. 2017 Academic Article GET IT
Times cited: 29
Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival. Molecular cancer research : MCR. 2017 Academic Article GET IT
Times cited: 22
Clinical and genetic determinants of ovarian metastases from colorectal cancer. Cancer. 2016 Academic Article GET IT
Times cited: 52
Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma. Oncotarget. 2016 Academic Article GET IT
Times cited: 23
Faster FOLFOX: Oxaliplatin Can Be Safely Infused at a Rate of 1 mg/m2/min. Journal of oncology practice. 2016 Academic Article GET IT
Times cited: 8
Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease. Gastroenterology. 2016 Academic Article GET IT
Times cited: 143
Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016 Academic Article GET IT
Times cited: 192
Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF. Molecular cancer research : MCR. 2015 Academic Article GET IT
Times cited: 42
Impact of somatic mutations on patterns of metastasis in colorectal cancer. Journal of gastrointestinal oncology. 2015 Information Resource GET IT
Times cited: 85
RAF plus EGFR Inhibition for BRAF-Mutant Metastatic Colorectal Cancer-Response. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Article GET IT
Times cited: 1
AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants. Molecular cancer research : MCR. 2015 Academic Article GET IT
Times cited: 23
Pilot trial of combined BRAF and EGFR inhibition in BRAF-mutant metastatic colorectal cancer patients. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Academic Article GET IT
Times cited: 236
RAS mutations affect pattern of metastatic spread and increase propensity for brain metastasis in colorectal cancer. Cancer. 2014 Academic Article GET IT
Times cited: 151
Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions. Genome biology. 2014 Academic Article GET IT
Times cited: 287
False-positive elevations of carcinoembryonic antigen in patients with a history of resected colorectal cancer. Journal of the National Comprehensive Cancer Network : JNCCN. 2014 Academic Article GET IT
Times cited: 83
BRAF mutation predicts for poor outcomes after metastasectomy in patients with metastatic colorectal cancer. Cancer. 2014 Academic Article GET IT
Times cited: 162
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence. Cancer research. 2014 Academic Article GET IT
Times cited: 250
BRAF mutations in colorectal cancer: clinical relevance and role in targeted therapy. Journal of the National Comprehensive Cancer Network : JNCCN. 2012 Article GET IT
Times cited: 12
Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature. 2012 Academic Article GET IT
Times cited: 1548
Comparing genetic ancestry and self-described race in african americans born in the United States and in Africa. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2008 Academic Article GET IT
Times cited: 105
17HSD 2 may be higher in African-American breast cancer and is associated with estrogen receptor-negative tumors. Cancer genomics & proteomics. 2007 Academic Article GET IT
Times cited: 4

VIVO Weill Cornell Medical College

Rona Yaeger Associate Professor of Medicine

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Publications

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