selected publications
- Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model. Neuron. 2024 Academic Article GET IT
- Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model. 2024 GET IT
- A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells. Journal of molecular cell biology. 2023 Academic Article GET IT
- Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders. Molecular neurodegeneration. 2023 Review GET IT
- DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity. 2023 GET IT
- DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity. 2023 GET IT
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Autophagy prevents microglial senescence.
Nature cell biology.
2023
Academic Article
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Times cited: 8 -
Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy.
Cell stem cell.
2023
Academic Article
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Times cited: 24 -
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Nature neuroscience.
2023
Academic Article
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Times cited: 32 - A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells. iScience. 2022 Academic Article GET IT
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New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia.
Current opinion in neurobiology.
2021
Review
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Times cited: 1 -
A human embryonic stem cell reporter line for monitoring chemical-induced cardiotoxicity.
Cardiovascular research.
2020
Academic Article
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Times cited: 16 -
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival.
Nature communications.
2018
Academic Article
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Times cited: 27 -
Discovery of a drug candidate for GLIS3-associated diabetes.
Nature communications.
2018
Academic Article
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Times cited: 49 -
A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages.
Cell stem cell.
2017
Academic Article
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Times cited: 164 -
ROCKII inhibition promotes the maturation of human pancreatic beta-like cells.
Nature communications.
2017
Academic Article
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Times cited: 73 -
Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.
Nature medicine.
2017
Academic Article
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Times cited: 311 -
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.
Cell stem cell.
2017
Academic Article
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Times cited: 136 -
Modeling Cystic Fibrosis Using Pluripotent Stem Cell-Derived Human Pancreatic Ductal Epithelial Cells.
Stem cells translational medicine.
2016
Academic Article
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Times cited: 43 -
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Proceedings of the National Academy of Sciences of the United States of America.
2013
Academic Article
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Times cited: 141