selected publications
- Development of a NanoBiT based high throughput screening assay for discovery of NOS1-NOS1AP interaction inhibitors. SLAS discovery : advancing life sciences R & D. 2026 Academic Article GET IT
- High-throughput fragment screening identifies a new small molecule scaffold that modulates TREM2 Signaling. Bioorganic & medicinal chemistry. 2026 Academic Article GET IT
- Exploiting NMR Ensemble Heterogeneity Enables Small Molecule Discovery Against Dynamic Protein-Protein Interfaces. 2026 GET IT
- Small-molecule TREM2 agonists: From artificial intelligence driven discovery to therapeutic application in Alzheimer's disease. Neural regeneration research. 2026 Academic Article GET IT
- Development of a NanoBiT based high throughput screening assay for discovery of NOS1-CAPON interaction inhibitors. 2026 GET IT
- Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer's Models. 2026 GET IT
- AI-Assisted Discovery and Optimization of Small-Molecule TREM2 Agonists with Functional Microglial Activity. ACS medicinal chemistry letters. 2026 Academic Article GET IT
- Structure-Based Virtual Screening Identifies TREM2-Targeted Small Molecules that Enhance Microglial Phagocytosis. ChemMedChem. 2026 Academic Article GET IT
- A large puncture closer of aortic wall by multi-memory actions with thrombo-hemodynamic control. Bioactive materials. 2025 Academic Article GET IT
- AI-guided design of cyclic peptide binders targeting TREM2 using CycleRFdiffusion and experimental validation. Bioorganic & medicinal chemistry letters. 2025 Academic Article GET IT
- Overcoming the undruggable barrier: Structure-guided discovery of a potent small molecule CD28 antagonist with translational potential. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2025 Academic Article GET IT
- As48, a first-in-class dual-function TREM2 modulator: Receptor activation and shedding inhibition. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2025 Academic Article GET IT
- HTS-Oracle: Experimentally validated AI-enabled prioritization for generalizable small molecule hit discovery. 2025 GET IT
- High-Throughput Fragment Screening Identifies a New Small Molecule Scaffold that Modulates TREM2 Signaling. 2025 GET IT
- Discovery of CD28-Targeted Small Molecule Inhibitors of T Cell Co-Stimulation Using Affinity Selection-Mass Spectrometry (AS-MS) and Ex Vivo Validation. Journal of medicinal chemistry. 2025 Academic Article GET IT
- TREM2 activation by first-in-class direct small molecule agonists: DEL screening, optimization, biophysical validation, and functional characterization. European journal of medicinal chemistry. 2025 Academic Article GET IT
- Structure-Guided Optimization and Functional Characterization of Small Molecule Antagonists Targeting CD28 Costimulation. 2025 GET IT
- Structure-based virtual screening identifies potent CD28 inhibitors that suppress T cell co-stimulation in cellular and mucosal models. European journal of medicinal chemistry. 2025 Academic Article GET IT
- AI-Assisted Discovery and Optimization of Small Molecule TREM2 Agonists with Functional Microglial Activity. 2025 GET IT
- As48, a First-in-Class Dual-Function TREM2 Modulator: Receptor Activation and Shedding Inhibition. 2025 GET IT
- Structure-Based Virtual Screening Identifies TREM2-Targeted Small Molecules that Enhance Microglial Phagocytosis. 2025 GET IT
- Discovery of CD28-Targeted Small Molecule Inhibitors of T Cell Co-stimulation Using Affinity Selection-Mass Spectrometry (AS-MS) and Ex Vivo Validation. 2025 GET IT
- Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement. ACS medicinal chemistry letters. 2025 Academic Article GET IT
- HTS-Oracle: A Retrainable AI Platform for High-Confidence Hit Identification Across Difficult-to-Drug Targets. 2025 GET IT
- Small Molecule-Based Blockade of CD28 Suppresses T Cell Costimulation Across Cellular and Mucosal Co-culture Models. 2025 GET IT
- Discovery of an Achiral Small Molecule TREM2 Agonist with Improved Pharmacokinetic Profile and Validated Target Engagement. 2025 GET IT
- TREM2 Activation by First-in-Class Direct Small Molecule Agonists: DEL Screening, Optimization, Biophysical Validation, and Functional Characterization. 2025 GET IT
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Chip collection of hepatocellular carcinoma based on O2 heterogeneity from patient tissue.
Nature communications.
2024
Academic Article
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Times cited: 9 -
Surface Crystal and Degradability of Shape Memory Scaffold Essentialize Osteochondral Regeneration.
Small (Weinheim an der Bergstrasse, Germany).
2024
Academic Article
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Times cited: 5 -
Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition.
Cell reports.
2022
Academic Article
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Times cited: 29 -
Diagnostic challenge of fetal ontogeny and its application on the ovarian teratomas.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.
2005
Academic Article
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Times cited: 6