selected publications
- Structure-based virtual screening identifies potent CD28 inhibitors that suppress T cell co-stimulation in cellular and mucosal models. European journal of medicinal chemistry. 2025 Academic Article GET IT
- AI-Assisted Discovery and Optimization of Small Molecule TREM2 Agonists with Functional Microglial Activity. 2025 GET IT
- As48, a First-in-Class Dual-Function TREM2 Modulator: Receptor Activation and Shedding Inhibition. 2025 GET IT
- Structure-Based Virtual Screening Identifies TREM2-Targeted Small Molecules that Enhance Microglial Phagocytosis. 2025 GET IT
- Discovery of CD28-Targeted Small Molecule Inhibitors of T Cell Co-stimulation Using Affinity Selection-Mass Spectrometry (AS-MS) and Ex Vivo Validation. 2025 GET IT
- Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement. ACS medicinal chemistry letters. 2025 Academic Article GET IT
- HTS-Oracle: A Retrainable AI Platform for High-Confidence Hit Identification Across Difficult-to-Drug Targets. 2025 GET IT
- Small Molecule-Based Blockade of CD28 Suppresses T Cell Costimulation Across Cellular and Mucosal Co-culture Models. 2025 GET IT
- Discovery of an Achiral Small Molecule TREM2 Agonist with Improved Pharmacokinetic Profile and Validated Target Engagement. 2025 GET IT
- TREM2 Activation by First-in-Class Direct Small Molecule Agonists: DEL Screening, Optimization, Biophysical Validation, and Functional Characterization. 2025 GET IT
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Chip collection of hepatocellular carcinoma based on O2 heterogeneity from patient tissue.
Nature communications.
2024
Academic Article
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Times cited: 3 -
Surface Crystal and Degradability of Shape Memory Scaffold Essentialize Osteochondral Regeneration.
Small (Weinheim an der Bergstrasse, Germany).
2024
Academic Article
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Times cited: 5 -
Diagnostic challenge of fetal ontogeny and its application on the ovarian teratomas.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.
2005
Academic Article
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Times cited: 6