selected publications Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer. Cancer cell. 2024 Academic Article GET IT Author Correction: Senolytic CAR T cells reverse senescence-associated pathologies. 2024 GET IT PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay. Developmental cell. 2021 Academic Article GET IT Times cited: 22 Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program. Molecular cell. 2020 Academic Article GET IT Times cited: 49 Senolytic CAR T cells reverse senescence-associated pathologies. Nature. 2020 Academic Article GET IT Times cited: 587 p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell. 2018 Academic Article GET IT Times cited: 289 DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT Times cited: 123 Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. eLife. 2016 Academic Article GET IT Times cited: 11 The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation. eLife. 2014 Academic Article GET IT Times cited: 35
Funding awarded Personalized in vitro models to advance precision health equity awarded by National Cancer Institute Co-Investigator 2024 - 2025 Delineating the role of genetic mutations in Hepatoblastoma development and phenotypes awarded by United States Department of Defense Co-Investigator 2021 - 2024
education and training Ph.D., Northwestern University Medical School 2014 B.A., New York University 2004