selected publications
- Organ-specific effects on glycolysis by the dioxin-activated aryl hydrocarbon receptor. PloS one. 2020 Academic Article GET IT
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NAD+ loss, a new player in AhR biology: prevention of thymus atrophy and hepatosteatosis by NAD+ repletion.
Scientific reports.
2017
Academic Article
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Times cited: 17 -
Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolase inhibitor AUDA.
Drug metabolism and disposition: the biological fate of chemicals.
2013
Academic Article
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Times cited: 12 -
Aryl hydrocarbon receptor activation by dioxin targets phosphoenolpyruvate carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP).
The Journal of biological chemistry.
2013
Academic Article
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Times cited: 20 -
Discovery and biological characterization of 1-(1H-indol-3-yl)-9H-pyrido[3,4-b]indole as an aryl hydrocarbon receptor activator generated by photoactivation of tryptophan by sunlight.
Chemico-biological interactions.
2011
Academic Article
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Times cited: 14 -
Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect.
The Journal of biological chemistry.
2010
Academic Article
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Times cited: 73 -
Mitochondrial P450-dependent arachidonic acid metabolism by TCDD-induced hepatic CYP1A5; conversion of EETs to DHETs by mitochondrial soluble epoxide hydrolase.
Archives of biochemistry and biophysics.
2007
Academic Article
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Times cited: 11 -
Induction of CYP1A and cyp2-mediated arachidonic acid epoxygenation and suppression of 20-hydroxyeicosatetraenoic acid by imidazole derivatives including the aromatase inhibitor vorozole.
Drug metabolism and disposition: the biological fate of chemicals.
2006
Academic Article
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Times cited: 22 -
Sunlight generates multiple tryptophan photoproducts eliciting high efficacy CYP1A induction in chick hepatocytes and in vivo.
Toxicological sciences : an official journal of the Society of Toxicology.
2005
Academic Article
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Times cited: 54 -
Cell-type specificity of ectonucleotidase expression and upregulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Archives of biochemistry and biophysics.
2002
Academic Article
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Times cited: 16