selected publications
- Obesity-induced Ly6CHigh and Ly6CLow monocyte subset changes abolish post-ischemic limb conditioning benefits in stroke recovery. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023 Academic Article GET IT
- Association between substantia nigra degeneration and functional outcome in patients with basal ganglia infarction. European journal of neurology. 2023 Academic Article GET IT
- 2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer's resilience. Neuron. 2023 Academic Article GET IT
- Endothelial cell CD36 mediates stroke-induced brain injury via BBB dysfunction and monocyte infiltration in normal and obese conditions. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023 Academic Article GET IT
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Association of Substantia Nigra Degeneration with Poor Neurological Recovery in Basal Ganglia Infarctions.
Journal of stroke.
2022
Academic Article
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Times cited: 3 -
Phagocytosis converts infiltrated monocytes to microglia-like phenotype in experimental brain ischemia.
Journal of neuroinflammation.
2022
Academic Article
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Times cited: 15 -
Delayed Infiltration of Peripheral Monocyte Contributes to Phagocytosis and Transneuronal Degeneration in Chronic Stroke.
Stroke.
2022
Academic Article
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Times cited: 17 -
Aflibercept, a VEGF (Vascular Endothelial Growth Factor)-Trap, Reduces Vascular Permeability and Stroke-Induced Brain Swelling in Obese Mice.
Stroke.
2021
Academic Article
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Times cited: 20 -
CNS and peripheral immunity in cerebral ischemia: partition and interaction.
Experimental neurology.
2020
Review
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Times cited: 24 -
Sustained Increases in Immune Transcripts and Immune Cell Trafficking During the Recovery of Experimental Brain Ischemia.
Stroke.
2020
Academic Article
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Times cited: 16 -
Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury.
Cell reports.
2020
Academic Article
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Times cited: 36 -
CD36 deficiency reduces chronic BBB dysfunction and scar formation and improves activity, hedonic and memory deficits in ischemic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2020
Academic Article
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Times cited: 20 -
An Increase of Excitatory-to-Inhibitory Synaptic Balance in the Contralateral Cortico-Striatal Pathway Underlies Improved Stroke Recovery in BDNF Val66Met SNP Mice.
Neurorehabilitation and neural repair.
2019
Academic Article
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Times cited: 11 -
Optimizing functional outcome endpoints for stroke recovery studies.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2019
Information Resource
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Times cited: 23 -
Remote Postischemic Conditioning Promotes Stroke Recovery by Shifting Circulating Monocytes to CCR2+ Proinflammatory Subset.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2019
Academic Article
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Times cited: 34 -
Corticosterone-Mediated Body Weight Loss Is an Important Catabolic Process for Poststroke Immunity and Survival.
Stroke.
2019
Academic Article
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Times cited: 10 -
Preventative, but not post-stroke, inhibition of CD36 attenuates brain swelling in hyperlipidemic stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2019
Academic Article
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Times cited: 13 - Peripheral Mechanisms of Remote Ischemic Conditioning. Conditioning medicine. 2019 Academic Article GET IT
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Genetics of stroke recovery: BDNF val66met polymorphism in stroke recovery and its interaction with aging.
Neurobiology of disease.
2018
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Times cited: 48 -
Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF-Val66Met variant.
The Journal of biological chemistry.
2018
Academic Article
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Times cited: 39 -
Dabigatran reduces endothelial permeability through inhibition of thrombin-induced cytoskeleton reorganization.
Thrombosis research.
2018
Academic Article
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Times cited: 5 -
What Do Experimental Models Teach Us About Comorbidities in Stroke?.
Stroke.
2018
Review
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Times cited: 19 -
Inhibition of VEGF Signaling Reduces Diabetes-Exacerbated Brain Swelling, but Not Infarct Size, in Large Cerebral Infarction in Mice.
Translational stroke research.
2017
Academic Article
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Times cited: 35 -
Microglia and Monocyte-Derived Macrophages in Stroke.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.
2016
Information Resource
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Times cited: 113 -
Cell Surface CD36 Protein in Monocyte/Macrophage Contributes to Phagocytosis during the Resolution Phase of Ischemic Stroke in Mice.
The Journal of biological chemistry.
2016
Academic Article
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Times cited: 99 -
Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice.
Neurobiology of aging.
2016
Academic Article
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Times cited: 28 -
Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.
Science translational medicine.
2016
Academic Article
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Times cited: 118 -
Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease.
Neurochemistry international.
2016
Academic Article
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Times cited: 23 -
Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2015
Academic Article
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Times cited: 48 -
Targeting CD36-mediated inflammation reduces acute brain injury in transient, but not permanent, ischemic stroke.
CNS neuroscience & therapeutics.
2014
Academic Article
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Times cited: 48 -
Role of spleen-derived monocytes/macrophages in acute ischemic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2014
Academic Article
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Times cited: 151 -
Deregulation of inflammatory response in the diabetic condition is associated with increased ischemic brain injury.
Journal of neuroinflammation.
2014
Academic Article
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Times cited: 45 -
An adaptive role for BDNF Val66Met polymorphism in motor recovery in chronic stroke.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2014
Academic Article
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Times cited: 82 -
CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia.
Annals of neurology.
2012
Academic Article
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Times cited: 48 -
Salvianolic acid B inhibits macrophage uptake of modified low density lipoprotein (mLDL) in a scavenger receptor CD36-dependent manner.
Atherosclerosis.
2012
Academic Article
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Times cited: 76 -
Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2012
Academic Article
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Times cited: 53 -
CD36 is involved in astrocyte activation and astroglial scar formation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2012
Academic Article
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Times cited: 91 -
Prohibitin reduces mitochondrial free radical production and protects brain cells from different injury modalities.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2012
Academic Article
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Times cited: 77 -
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.
Proceedings of the National Academy of Sciences of the United States of America.
2011
Academic Article
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Times cited: 137 -
Genetic variant of BDNF (Val66Met) polymorphism attenuates stroke-induced angiogenic responses by enhancing anti-angiogenic mediator CD36 expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2011
Academic Article
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Times cited: 69 -
A role for spleen monocytes in post-ischemic brain inflammation and injury.
Journal of neuroinflammation.
2010
Academic Article
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Times cited: 80 -
Ischemic preconditioning-induced neuroprotection is associated with differential expression of IL-1beta and IL-1 receptor antagonist in the ischemic cortex.
Journal of neuroimmunology.
2009
Academic Article
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Times cited: 29 -
CD36/fatty acid translocase, an inflammatory mediator, is involved in hyperlipidemia-induced exacerbation in ischemic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2008
Academic Article
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Times cited: 81 -
Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2008
Academic Article
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Times cited: 133 -
Harnessing hypoxic adaptation to prevent, treat, and repair stroke.
Journal of molecular medicine (Berlin, Germany).
2007
Information Resource
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Times cited: 79 -
A novel cell-permeable antioxidant peptide, SS31, attenuates ischemic brain injury by down-regulating CD36.
The Journal of biological chemistry.
2006
Academic Article
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Times cited: 135 -
Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2006
Academic Article
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Times cited: 30 -
Enhanced ERK dependent CREB activation reduces apoptosis in staurosporine-treated human neuroblastoma SK-N-BE(2)C cells.
Neuroscience letters.
2006
Academic Article
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Times cited: 15 -
Inducible nitric oxide synthase contributes to gender differences in ischemic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2006
Academic Article
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Times cited: 102 -
Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity.
Nature medicine.
2006
Academic Article
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Times cited: 313 -
Obligatory role of inducible nitric oxide synthase in ischemic preconditioning.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2005
Academic Article
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Times cited: 100 -
The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2005
Academic Article
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Times cited: 188 -
Ibuprofen protects ischemia-induced neuronal injury via up-regulating interleukin-1 receptor antagonist expression.
Neuroscience.
2005
Academic Article
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Times cited: 41 -
Interaction between inducible nitric oxide synthase and poly(ADP-ribose) polymerase in focal ischemic brain injury.
Stroke.
2004
Academic Article
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Times cited: 65 -
A neuroprotective role of extracellular signal-regulated kinase in N-acetyl-O-methyldopamine-treated hippocampal neurons after exposure to in vitro and in vivo ischemia.
Neuroscience.
2004
Academic Article
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Times cited: 44 -
Microglial phagocytosis of dopamine neurons at early phases of apoptosis.
Cellular and molecular neurobiology.
2003
Academic Article
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Times cited: 22 -
Temporal and sequential analysis of microglia in the substantia nigra following medial forebrain bundle axotomy in rat.
Neuroscience.
2003
Academic Article
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Times cited: 42 -
Early c-Fos induction after cerebral ischemia: a possible neuroprotective role.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2001
Academic Article
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Times cited: 52 -
Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: protein kinase A-dependent mechanism.
Glia.
2001
Academic Article
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Times cited: 37 -
Altered presynaptic gene expression in transgenic mice producing dopamine in the pineal gland.
Synapse (New York, N.Y.).
1999
Academic Article
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Times cited: 3 -
Blockade of tetrahydrobiopterin synthesis protects neurons after transient forebrain ischemia in rat: a novel role for the cofactor.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1999
Academic Article
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Times cited: 53 -
Neuroprotection and neuronal differentiation studies using substantia nigra dopaminergic cells derived from transgenic mouse embryos.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
1999
Academic Article
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Times cited: 173 -
Melatonin administration protects CA1 hippocampal neurons after transient forebrain ischemia in rats.
Brain research.
1997
Academic Article
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Times cited: 98 -
Reduced sympathetic innervation after alteration of target cell neurotransmitter phenotype in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America.
1996
Academic Article
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Times cited: 10