selected publications
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APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons.
Nature communications.
2025
Academic Article
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Times cited: 1 -
Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nature structural & molecular biology.
2023
Academic Article
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Times cited: 13 - The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activity. Molecular biology of the cell. 2023 Academic Article GET IT
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Frozen in time: analyzing molecular dynamics with time-resolved cryo-EM.
Structure (London, England : 1993).
2022
Review
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Times cited: 39 -
Examining the mechanistic relationship of APC/CCDH1 and its interphase inhibitor EMI1.
Protein science : a publication of the Protein Society.
2022
Academic Article
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Times cited: 7 -
APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain.
Molecular cell.
2021
Academic Article
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Times cited: 9 -
Intricate Regulatory Mechanisms of the Anaphase-Promoting Complex/Cyclosome and Its Role in Chromatin Regulation.
Frontiers in cell and developmental biology.
2021
Review
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Times cited: 15 -
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming.
Nature structural & molecular biology.
2020
Academic Article
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Times cited: 34 -
Quantifying the heterogeneity of macromolecular machines by mass photometry.
Nature communications.
2020
Academic Article
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Times cited: 146 -
Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20.
Nature chemical biology.
2020
Academic Article
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Times cited: 25 -
The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
eLife.
2020
Academic Article
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Times cited: 32 - UBE2S Learns Self-Control. Structure (London, England : 1993). 2019 Comment GET IT