Sanchez Garcia Vao, Teresa

Affiliation

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Laboratory of Molecular and Translational Vascular Research Principal Investigator

Publications

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selected publications

Molecular and Functional Alterations in the Cerebral Microvasculature in an Optimized Mouse Model of Sepsis-Associated Cognitive Dysfunction. eNeuro. 2024 Academic Article GET IT
Times cited: 4
Molecular and functional alterations in the cerebral microvasculature in an optimized mouse model of sepsis-associated cognitive dysfunction. 2024 GET IT
Molecular and functional alterations in the cerebral microvasculature in an optimized mouse model of sepsis-associated cognitive dysfunction. bioRxiv. https://www.biorxiv.org/content/10.1101/2024.05.28.596050v1. 2024 Academic Article
Molecular profiling of the stroke-induced alterations in the cerebral microvasculature reveals promising therapeutic candidates. Proceedings of the National Academy of Sciences of the United States of America. 2023 Academic Article GET IT
Times cited: 14
Vascular oxidative stress causes neutrophil arrest in brain capillaries, leading to decreased cerebral blood flow and contributing to memory impairment in a mouse model of Alzheimerâ€™s disease. 2023 GET IT
Vascular oxidative stress causes neutrophil arrest in brain capillaries, leading to decreased cerebral blood flow and contributing to memory impairment in a mouse model of Alzheimer’s disease. https://doi.org/10.1101/2023.02.15.528710. BioRxiv. 2023 Academic Article
Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification. Nature communications. 2021 Academic Article GET IT
Times cited: 35
Endothelial S1P₁ Signaling Counteracts Infarct Expansion in Ischemic Stroke. Circulation research. 2020 Academic Article GET IT
Times cited: 104
The isolation and molecular characterization of cerebral microvessels. Nature protocols. 2019 Academic Article GET IT
Times cited: 84
Evaluation of S1PR1, pSTAT3, S1PR2, FOXP1 Expression in Aggressive, Mature B Cell Lymphomas. Journal of hematopathology. 2019 Academic Article GET IT
Times cited: 6
An engineered S1P chaperone attenuates hypertension and ischemic injury. Science signaling. 2017 Academic Article GET IT
Times cited: 92
Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. Proceedings of the National Academy of Sciences of the United States of America. 2017 Academic Article GET IT
Times cited: 174
Sphingosine-1-Phosphate Signaling in Endothelial Disorders. Current atherosclerosis reports. 2016 Review GET IT
Times cited: 23
Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke. Nature communications. 2015 Academic Article GET IT
Times cited: 130
Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation. Blood. 2013 Academic Article GET IT
Times cited: 154
Sphingosine-1-phosphate receptor 1 in classical Hodgkin lymphoma: assessment of expression and role in cell migration. Laboratory investigation; a journal of technical methods and pathology. 2013 Academic Article GET IT
Times cited: 39
S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor. The Journal of urology. 2009 Academic Article GET IT
Times cited: 26
S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor. Cancer letters. 2009 Academic Article GET IT
Times cited: 54
Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2. Molecular cancer research : MCR. 2008 Academic Article GET IT
Times cited: 60
Up-regulating sphingosine 1-phosphate receptor-2 signaling impairs chemotactic, wound-healing, and morphogenetic responses in senescent endothelial cells. The Journal of biological chemistry. 2008 Academic Article GET IT
Times cited: 44
Essential role of sphingosine 1-phosphate receptor 2 in pathological angiogenesis of the mouse retina. The Journal of clinical investigation. 2007 Academic Article GET IT
Times cited: 197
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. Arteriosclerosis, thrombosis, and vascular biology. 2007 Academic Article GET IT
Times cited: 220
Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization. Cancer research. 2006 Academic Article GET IT
Times cited: 237
GR 63799X, an EP3 receptor agonist, induced S phase arrest and 3T6 fibroblast growth inhibition. European journal of pharmacology. 2005 Academic Article GET IT
Times cited: 11
PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. Proceedings of the National Academy of Sciences of the United States of America. 2005 Academic Article GET IT
Times cited: 137
Structural and functional characteristics of S1P receptors. Journal of cellular biochemistry. 2004 Review GET IT
Times cited: 384
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability. The Journal of biological chemistry. 2003 Academic Article GET IT
Times cited: 341
Calcium-independent phospholipase A2 through arachidonic acid mobilization is involved in Caco-2 cell growth. Journal of cellular physiology. 2002 Academic Article GET IT
Times cited: 37
Role of EP(1) and EP(4) PGE(2) subtype receptors in serum-induced 3T6 fibroblast cycle progression and proliferation. American journal of physiology. Cell physiology. 2002 Academic Article GET IT
Times cited: 36
Role of phospholipases A(2) in growth-dependent changes in prostaglandin release from 3T6 fibroblasts. Journal of cellular physiology. 2001 Academic Article GET IT
Times cited: 10
Olive oil decreases both oxidative stress and the production of arachidonic acid metabolites by the prostaglandin G/H synthase pathway in rat macrophages. The Journal of nutrition. 2001 Academic Article GET IT
Times cited: 63
The effect of high molecular phospholipase A2 inhibitors on 3T6 fibroblast proliferation. Biochemical pharmacology. 2001 Academic Article GET IT
Times cited: 24
Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase. The Journal of biological chemistry. 2000 Academic Article GET IT
Times cited: 69
Regulation of prostaglandin E2 production by the superoxide radical and nitric oxide in mouse peritoneal macrophages. Free radical research. 2000 Academic Article GET IT
Times cited: 42
Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin. Biochemical pharmacology. 1999 Academic Article GET IT
Times cited: 36
Role of prostaglandin H synthase isoforms in murine ear edema induced by phorbol ester application on skin. Prostaglandins & other lipid mediators. 1999 Academic Article GET IT
Times cited: 27
Ketoprofen S(+) enantiomer inhibits prostaglandin production and cell growth in 3T6 fibroblast cultures. European journal of pharmacology. 1999 Academic Article GET IT
Times cited: 18
Induction by interleukin-1beta peptide of prostaglandin E2 formation via enhanced prostaglandin H synthase-2 expression in 3T6 fibroblasts. Biochemical pharmacology. 1998 Academic Article GET IT
Times cited: 4
Role of prostaglandin H synthase-2-mediated conversion of arachidonic acid in controlling 3T6 fibroblast growth. The American journal of physiology. 1997 Academic Article GET IT
Times cited: 39

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Research

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Funding awarded

Unraveling Mechanisms and Novel Therapeutic Strategies in Cerebral Microvascular Dysfunction and Cognitive Impairment. Principal Investigator 2025 - 2030
Role and therapeutic targeting of the cerebral microvasculature in dementia awarded by Alzheimer''s Association National Office Principal Investigator 2025 - 2028
Biopharma Agreement with Sanofi S.A awarded by Sanofi S.A. Principal Investigator 2025 - 2026
Endothelial Sphingolipid Signaling in Neurovascular Ischemic Injury awarded by National Institute of Neurological Disorders & Stroke Principal Investigator 2020 - 2026
missing activity Principal Investigator 2022 - 2025

Stalled Capillary Flow: a Novel Mechanism for Hypoperfusion in Alzheimer's Disease Co-Principal Investigator

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Background

education and training

Pharm.B., University of Barcelona (Spain) 96
Ph.D., University of Barcelona (Spain) 2001
M.S., University of Barcelona (Spain) 1997

Contact

full name

Teresa Sanchez Garcia Vao

primary email

tes2015@med.cornell.edu

webpage

Laboratory of Molecular and Translational Vascular Research

VIVO Weill Cornell Medical College

Teresa Sanchez Garcia Vao Associate Professor of Pathology and Laboratory Medicine

Affiliation

head of

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage

Phone

Affiliation

head of

Publications

selected publications

Research

Funding awarded

Background

education and training

Contact

full name

primary email

webpage