selected publications
- Addition to "Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation". 2024 GET IT
- Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. Journal of chemical information and modeling. 2023 Academic Article GET IT
- Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory in mice and is neuroprotective in pigs. The Journal of biological chemistry. 2023 Academic Article GET IT
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On-demand male contraception via acute inhibition of soluble adenylyl cyclase.
Nature communications.
2023
Academic Article
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Times cited: 18 -
Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates.
Journal of medicinal chemistry.
2022
Academic Article
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Times cited: 8 -
Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential.
Frontiers in physiology.
2022
Academic Article
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Times cited: 4 -
Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization.
Molecular human reproduction.
2021
Academic Article
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Times cited: 24 -
Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10).
ACS medicinal chemistry letters.
2021
Academic Article
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Times cited: 14 -
Bicarbonate, carbon dioxide and pH sensing via mammalian bicarbonate-regulated soluble adenylyl cyclase.
Interface focus.
2021
Review
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Times cited: 18