selected publications
- Metabolic rewiring of isoniazid sensitivity in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 2025 Academic Article GET IT
- Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis. mBio. 2025 Academic Article GET IT
- Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action. Cell systems. 2025 Academic Article GET IT
- RNA polymerase-mediated regulation of intrinsic antibiotic resistance and bacterial cell division. 2025 GET IT
- Editorial: Metabolomics in bacterial infections. Frontiers in cellular and infection microbiology. 2025 Editorial Article GET IT
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Functional characterization of MMAR_1296 in Mycobacterium marinum and its potential as a vaccine candidate.
Vaccine.
2025
Academic Article
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Times cited: 2 - Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis. 2024 GET IT
- Decoding Serum Metabolic Secrets of Nontuberculous Mycobacterial Pulmonary Disease. The Journal of infectious diseases. 2024 Editorial Article GET IT
- Editorial: Systems biology and antimicrobial drug resistance. Frontiers in microbiology. 2024 Editorial Article GET IT
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The Bacillus subtilis yqgC-sodA operon protects magnesium-dependent enzymes by supporting manganese efflux.
Journal of bacteriology.
2024
Academic Article
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Times cited: 2 - The Bacillus subtilis yqgC-sodA operon protects magnesium-dependent enzymes by supporting manganese efflux. 2024 GET IT
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Metabolic Rewiring of Mycobacterium tuberculosis upon Drug Treatment and Antibiotics Resistance.
Metabolites.
2024
Review
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Times cited: 9 -
Mycobacterium smegmatis, a Promising Vaccine Vector for Preventing TB and Other Diseases: Vaccinomics Insights and Applications.
Vaccines.
2023
Review
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Times cited: 9 -
Insights into the central role of N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU) in peptidoglycan metabolism and its potential as a therapeutic target.
The Biochemical journal.
2023
Review
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Times cited: 4 -
Editorial: Bacterial metabolomics approach towards antimicrobials and resistance.
Frontiers in microbiology.
2023
Editorial Article
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Times cited: 2 -
Mutations in rpoB That Confer Rifampicin Resistance Can Alter Levels of Peptidoglycan Precursors and Affect β-Lactam Susceptibility.
mBio.
2023
Academic Article
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Times cited: 25 -
Therapeutic Potentials of Immunometabolomic Modulations Induced by Tuberculosis Vaccination.
Vaccines.
2022
Review
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Times cited: 8 -
Immunotherapy: an alternative promising therapeutic approach against cancers.
Molecular biology reports.
2022
Review
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Times cited: 62 -
B-Cell-Based Immunotherapy: A Promising New Alternative.
Vaccines.
2022
Review
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Times cited: 26 - Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy. Proceedings of the National Academy of Sciences of the United States of America. 2022 Academic Article GET IT
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A hydrogel-based implantable multidrug antitubercular formulation outperforms oral delivery.
Nanoscale.
2021
Academic Article
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Times cited: 6 -
Unique C-terminal extension and interactome of Mycobacterium tuberculosis GlmU impacts it's in vivo function and the survival of pathogen.
The Biochemical journal.
2021
Academic Article
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Times cited: 4 -
Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis.
Nature microbiology.
2020
Academic Article
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Times cited: 15 -
Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline.
Proceedings of the National Academy of Sciences of the United States of America.
2019
Academic Article
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Times cited: 43 -
The bifunctional protein GlmU is a key factor in biofilm formation induced by alkylating stress in Mycobacterium smegmatis.
Research in microbiology.
2019
Academic Article
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Times cited: 14 -
Oral Delivery of Cholic Acid-Derived Amphiphile Helps in Combating Salmonella-Mediated Gut Infection and Inflammation.
Bioconjugate chemistry.
2019
Academic Article
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Times cited: 29 -
Computational Sampling and Simulation Based Assessment of Novel Mycobacterium tuberculosis Glutamine Synthetase Inhibitors: Study Involving Structure Based Drug Design and Free Energy Perturbation.
Current topics in medicinal chemistry.
2016
Academic Article
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Times cited: 8 -
Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen.
PLoS pathogens.
2015
Academic Article
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Times cited: 34 -
Discovery of novel lysine ɛ-aminotransferase inhibitors: An intriguing potential target for latent tuberculosis.
Tuberculosis (Edinburgh, Scotland).
2015
Academic Article
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Times cited: 15 -
Structure-based design of diverse inhibitors of Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase: combined molecular docking, dynamic simulation, and biological activity.
Journal of molecular modeling.
2015
Academic Article
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Times cited: 15 -
Structure-based virtual screening as a tool for the identification of novel inhibitors against Mycobacterium tuberculosis 3-dehydroquinate dehydratase.
Journal of molecular graphics & modelling.
2015
Academic Article
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Times cited: 15 -
Targeting NAMPT for Therapeutic Intervention in Cancer and Inflammation: Structure-Based Drug Design and Biological Screening.
Chemical biology & drug design.
2015
Academic Article
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Times cited: 12 -
Identification of potential Mycobacterium tuberculosis topoisomerase I inhibitors: a study against active, dormant and resistant tuberculosis.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2015
Academic Article
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Times cited: 15 -
rpoS-Regulated core genes involved in the competitive fitness of Salmonella enterica Serovar Kentucky in the intestines of chickens.
Applied and environmental microbiology.
2014
Academic Article
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Times cited: 34 -
Structure-guided design and development of novel benzimidazole class of compounds targeting DNA gyraseB enzyme of Staphylococcus aureus.
Bioorganic & medicinal chemistry.
2014
Academic Article
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Times cited: 18 -
Development of novel N-linked aminopiperidine-based mycobacterial DNA gyrase B inhibitors: scaffold hopping from known antibacterial leads.
International journal of antimicrobial agents.
2013
Academic Article
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Times cited: 33 -
Thiazole-aminopiperidine hybrid analogues: design and synthesis of novel Mycobacterium tuberculosis GyrB inhibitors.
European journal of medicinal chemistry.
2013
Academic Article
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Times cited: 66 -
Identification of novel inhibitors against Mycobacterium tuberculosis L-alanine dehydrogenase (MTB-AlaDH) through structure-based virtual screening.
Journal of molecular graphics & modelling.
2013
Academic Article
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Times cited: 38 -
Substrate-bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine 1-phosphate uridyltransferase and a catalytic mechanism for acetyl transfer.
The Journal of biological chemistry.
2012
Academic Article
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Times cited: 24