selected publications
- Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM. Journal of the American Chemical Society. 2023 Academic Article GET IT
- Simultaneous estimation of the cellular water exchange rate, intracellular volume fraction, and longitudinal relaxation rate in cancer cells. NMR in biomedicine. 2023 Academic Article GET IT
- Post-translational modifications within tau paired helical filament nucleating motifs perturb microtubule interactions and oligomer formation. The Journal of biological chemistry. 2021 Academic Article GET IT
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Acyl-Coenzyme A Thioesterase 9 Traffics Mitochondrial Short-Chain Fatty Acids Toward De Novo Lipogenesis and Glucose Production in the Liver.
Hepatology (Baltimore, Md.).
2020
Academic Article
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Times cited: 4 -
Zinc induced structural changes in the intrinsically disordered BDNF Met prodomain confer synaptic elimination.
Metallomics : integrated biometal science.
2020
Academic Article
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Times cited: 1 -
Use of paramagnetic 19F NMR to monitor domain movement in a glutamate transporter homolog.
Nature chemical biology.
2020
Academic Article
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Times cited: 30 -
The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior.
Neuron.
2018
Academic Article
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Times cited: 41 -
NMR backbone resonance assignments of the prodomain variants of BDNF in the urea denatured state.
Biomolecular NMR assignments.
2017
Academic Article
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Times cited: 3 -
Structural Model of the Extracellular Assembly of the TCR-CD3 Complex.
Cell reports.
2016
Academic Article
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Times cited: 40 -
Evaluation of the Relative Performance of Drug-Induced Skeletal Muscle Injury Biomarkers in Rats.
Toxicological sciences : an official journal of the Society of Toxicology.
2015
Academic Article
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Times cited: 24 -
Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly.
Molecular cell.
2013
Academic Article
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Times cited: 142 -
Assessment of the abuse liability of ABT-288, a novel histamine H₃ receptor antagonist.
Psychopharmacology.
2013
Academic Article
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Times cited: 8 -
Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction.
Nature communications.
2013
Academic Article
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Times cited: 177 -
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials.
Proceedings of the National Academy of Sciences of the United States of America.
2012
Academic Article
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Times cited: 94 -
Assembling ligands in situ using bioorthogonal boronate ester synthesis.
Chemistry & biology.
2010
Academic Article
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Times cited: 32 -
Sevoflurane binds and allosterically blocks integrin lymphocyte function-associated antigen-1.
Anesthesiology.
2010
Academic Article
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Times cited: 54 -
The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2008
Academic Article
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Times cited: 42 -
Trapping a folding intermediate of the alpha-helix: stabilization of the pi-helix.
Biochemistry.
2008
Academic Article
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Times cited: 26 -
Spin relaxation enhancement confirms dominance of extended conformations in short alanine peptides.
Angewandte Chemie (International ed. in English).
2007
Academic Article
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Times cited: 27 -
Polyproline II propensities from GGXGG peptides reveal an anticorrelation with beta-sheet scales.
Proceedings of the National Academy of Sciences of the United States of America.
2005
Academic Article
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Times cited: 146 -
NMR investigation of main-chain dynamics of the H80E mutant of bovine neurophysin-I: demonstration of dimerization-induced changes at the hormone-binding site.
Biochemistry.
2005
Academic Article
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Times cited: 3 -
pH dependence of amide chemical shifts in natively disordered polypeptides detects medium-range interactions with ionizable residues.
Biophysical journal.
2005
Academic Article
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Times cited: 16 -
Helix formation and the unfolded state of a 52-residue helical protein.
Protein science : a publication of the Protein Society.
2004
Academic Article
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Times cited: 19 -
An effective method for the discrimination of motional anisotropy and chemical exchange.
Journal of the American Chemical Society.
2002
Academic Article
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Times cited: 116 -
A method for efficient isotopic labeling of recombinant proteins.
Journal of biomolecular NMR.
2001
Academic Article
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Times cited: 578 -
The DNA-binding domain in the Bacillus subtilis transition-state regulator AbrB employs significant motion for promiscuous DNA recognition.
Journal of molecular biology.
2001
Academic Article
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Times cited: 21 -
NMR spin relaxation methods for characterization of disorder and folding in proteins.
Journal of molecular graphics & modelling.
2001
Academic Article
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Times cited: 39 -
Buried polar interactions and conformational stability in the simian immunodeficiency virus (SIV) gp41 core.
Biochemistry.
2000
Academic Article
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Times cited: 28 -
Characterization of millisecond time-scale dynamics in the molten globule state of alpha-lactalbumin by NMR.
Journal of molecular biology.
1999
Academic Article
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Times cited: 35 -
Temperature dependence of intramolecular dynamics of the basic leucine zipper of GCN4: implications for the entropy of association with DNA.
Journal of molecular biology.
1999
Academic Article
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Times cited: 195 -
CO_H(N)CACB experiments for assigning backbone resonances in 13C/15N-labeled proteins.
Journal of biomolecular NMR.
1998
Academic Article
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Times cited: 4 -
(H)N(COCA)NH and HN(COCA)NH experiments for 1H-15N backbone assignments in 13C/15N-labeled proteins.
Journal of biomolecular NMR.
1997
Academic Article
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Times cited: 39 -
Alpha-helix to random coil transitions of two-chain coiled coils: experiments on the thermal denaturation of beta beta tropomyosin cross-linked selectively at C36.
Biopolymers.
1990
Academic Article
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Times cited: 15 -
Alpha-helix-to-random-coil transitions of two-chain coiled coils: experiments on the thermal denaturation of beta beta tropomyosin cross-linked selectively at C-190.
Biopolymers.
1988
Academic Article
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Times cited: 15