selected publications
- Xenografted human iPSC-derived neurons with the familial Alzheimer's disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator. Acta neuropathologica. 2024 Academic Article GET IT
- Deletion of Small GTPase H-Ras Rescues Memory Deficits and Reduces Amyloid Plaque-Associated Dendritic Spine Loss in Transgenic Alzheimer's Mice. Molecular neurobiology. 2022 Academic Article GET IT
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Molecular Insights into Cell Type-specific Roles in Alzheimer's Disease: Human Induced Pluripotent Stem Cell-based Disease Modelling.
Neuroscience.
2022
Review
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Times cited: 6 -
Microglial TREM2 at the Intersection of Brain Aging and Alzheimer's Disease.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
2021
Review
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Times cited: 5 -
Metabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells.
Scientific reports.
2021
Academic Article
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Times cited: 9 -
Loss of TREM2 Confers Resilience to Synaptic and Cognitive Impairment in Aged Mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2020
Academic Article
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Times cited: 35 -
Neuronal Protein Farnesylation Regulates Hippocampal Synaptic Plasticity and Cognitive Function.
Molecular neurobiology.
2020
Academic Article
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Times cited: 17 -
Peripheral versus central nervous system APOE in Alzheimer's disease: Interplay across the blood-brain barrier.
Neuroscience letters.
2019
Review
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Times cited: 42 -
Astroglia contribute to the pathogenesis of spinocerebellar ataxia Type 1 (SCA1) in a biphasic, stage-of-disease specific manner.
Glia.
2018
Academic Article
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Times cited: 31 -
Inhibition of NF-κB signaling in IKKβF/F;LysM Cre mice causes motor deficits but does not alter pathogenesis of Spinocerebellar ataxia type 1.
PloS one.
2018
Academic Article
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Times cited: 19 -
Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice.
Journal of neuroinflammation.
2017
Academic Article
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Times cited: 45