selected publications
- Editor's Note: PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR. 2025 GET IT
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Elucidating the Cell Surfaceome to Accelerate Cancer Drug Development.
Cancer discovery.
2024
Academic Article
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Times cited: 9 -
The NIH-led research response to COVID-19.
Science (New York, N.Y.).
2023
Academic Article
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Times cited: 37 -
Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib.
Journal of medicinal chemistry.
2022
Academic Article
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Times cited: 24 -
Paradigms for the development of transformative medicines-lessons from the EGFR story.
Annals of oncology : official journal of the European Society for Medical Oncology.
2022
Editorial Article
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Times cited: 3 -
Catalyzing the field of precision oncology, one basket at a time.
Nature medicine.
2018
Academic Article
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Times cited: 3 -
Tissue-Specific Immunoregulation: A Call for Better Understanding of the "Immunostat" in the Context of Cancer.
Cancer discovery.
2018
Review
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Times cited: 71 -
Twice weekly pulse and daily continuous-dose erlotinib as initial treatment for patients with epidermal growth factor receptor-mutant lung cancers and brain metastases.
Cancer.
2017
Academic Article
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Times cited: 29 -
From academia to industry: a road more travelled.
Annals of oncology : official journal of the European Society for Medical Oncology.
2017
Academic Article
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Times cited: 4 -
Continued use of afatinib with the addition of cetuximab after progression on afatinib in patients with EGFR mutation-positive non-small-cell lung cancer and acquired resistance to gefitinib or erlotinib.
Lung cancer (Amsterdam, Netherlands).
2017
Academic Article
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Times cited: 11 -
SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer.
Cancer research.
2017
Academic Article
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Times cited: 118 -
Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors.
Molecular oncology.
2017
Academic Article
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Times cited: 29 -
Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies.
Genome medicine.
2017
Academic Article
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Times cited: 52 -
Phase 1 study of twice weekly pulse dose and daily low-dose erlotinib as initial treatment for patients with EGFR-mutant lung cancers.
Annals of oncology : official journal of the European Society for Medical Oncology.
2017
Academic Article
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Times cited: 41 -
AACR Cancer Progress Report 2016.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016
Academic Article
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Times cited: 36