Jiang, Ziyuan

Publications

Sort by

Co-Author Network

The pathogenic E139D mutation stabilizes a non-canonical active state of the multi-domain phosphatase SHP2. 2025 GET IT
Multiplexed single-cell transcriptomics reveals diverse phenotypic outcomes for pathogenic SHP2 variants. 2025 GET IT
Deep mutational scanning of the multi-domain phosphatase SHP2 reveals mechanisms of regulation and pathogenicity. Nature communications. 2025 Academic Article GET IT
Times cited: 1
Proximity-labeling proteomics reveals remodeled interactomes and altered localization of pathogenic SHP2 variants. 2025 GET IT
Allosteric inhibition rescues hydrocephalus caused by catalytically inactive Shp2. 2025 GET IT
Deep mutational scanning of a multi-domain signaling protein reveals mechanisms of regulation and pathogenicity. 2024 GET IT
The pathogenic T42A mutation in SHP2 rewires the interaction specificity of its N-terminal regulatory domain. Proceedings of the National Academy of Sciences of the United States of America. 2024 Academic Article GET IT
Times cited: 5
The pathogenic T42A mutation in SHP2 rewires the interaction specificity of its N-terminal regulatory domain. 2024 GET IT