publication venue for
- Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis.. 16. 2024
- Commensal antimicrobial resistance mediates microbiome resilience to antibiotic disruption.. 16. 2024
- Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML.. 16. 2024
- Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts.. 15. 2023
- Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.. 15. 2023
- Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse.. 15. 2023
- Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphoma.. 15. 2023
- Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer.. 15. 2023
- Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2.. 15. 2023
- Activation of MAP2K signaling by genetic engineering or HF-rTMS promotes corticospinal axon sprouting and functional regeneration.. 15. 2023
- Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge one year later. 2022
- Metabolic modulation of synaptic failure and thalamocortical hypersynchronization with preserved consciousness in Glut1 deficiency.. 14. 2022
- SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery.. 14. 2022
- Adenoviral-based vaccine promotes neoantigen-specific CD8+ T cell stemness and tumor rejection.. 14. 2022
- Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine.. 14. 2022
- MAIT and Vδ2 unconventional T cells are supported by a diverse intestinal microbiome and correlate with favorable patient outcome after allogeneic HCT.. 14. 2022
- Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non-small cell lung cancer.. 14. 2022
- Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia.. 14. 2022
- Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice.. 14. 2022
- Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits.. 14. 2022
- Combining a CAR and a chimeric costimulatory receptor enhances T cell sensitivity to low antigen density and promotes persistence.. 13. 2021
- AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.. 13. 2021
- Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected.. 13. 2021
- Ectopic activation of the miR-200c-EpCAM axis enhances antitumor T cell responses in models of adoptive cell therapy.. 13. 2021
- LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade.. 13. 2021
- Chop/Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice.. 13. 2021
- First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes.. 13. 2021
- Radiotherapy and immunotherapy converge on elimination of tumor-promoting erythroid progenitor cells through adaptive immunity.. 13. 2021
- Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans.. 12. 2020
- Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2.. 12. 2020
- Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans.. 12. 2020
- Using influenza surveillance networks to estimate state-specific prevalence of SARS-CoV-2 in the United States.. 12. 2020
- ATRAID regulates the action of nitrogen-containing bisphosphonates on bone.. 12. 2020
- Combined nucleus pulposus augmentation and annulus fibrosus repair prevents acute intervertebral disc degeneration after discectomy.. 12. 2020
- Interdomain spacing and spatial configuration drive the potency of IgG-[L]-scFv T cell bispecific antibodies.. 12. 2020
- DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes.. 11. 2019
- A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough.. 11. 2019
- Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment.. 11. 2019
- CAR T cells targeting BAFF-R can overcome CD19 antigen loss in B cell malignancies.. 11. 2019
- Muscarinic acetylcholine receptor regulates self-renewal of early erythroid progenitors.. 11. 2019
- Overcoming adaptive therapy resistance in AML by targeting immune response pathways.. 11. 2019
- Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species.. 11. 2019
- The androgen receptor regulates a druggable translational regulon in advanced prostate cancer.. 11. 2019
- The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells.. 11. 2019
- Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis.. 11. 2019
- Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease.. 11. 2019
- Primary cilia defects causing mitral valve prolapse.. 11. 2019
- HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness.. 11. 2019
- GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells.. 11. 2019
- Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer.. 11. 2019
- Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency.. 11. 2019
- Gene therapy reduces Parkinson's disease symptoms by reorganizing functional brain connectivity.. 10. 2018
- Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis.. 10. 2018
- An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo.. 10. 2018
- Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals.. 10. 2018
- Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant.. 10. 2018
- Thrombopoietin receptor-independent stimulation of hematopoietic stem cells by eltrombopag.. 10. 2018
- A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.. 10. 2018
- MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma.. 10. 2018
- Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.. 10. 2018
- A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice.. 10. 2018
- Targeting protein biotinylation enhances tuberculosis chemotherapy.. 10. 2018
- Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke.. 10. 2018
- Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8.. 10. 2018
- Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel.. 9. 2017
- Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.. 9. 2017
- Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis.. 9. 2017
- Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.. 9. 2017
- Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice.. 9. 2017
- In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease.. 9. 2017
- Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.. 9. 2017
- Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma.. 9. 2017
- RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury.. 9. 2017
- Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.. 9. 2017
- Influenza vaccines differentially regulate the interferon response in human dendritic cell subsets.. 9. 2017
- IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote TH17-dependent inflammation.. 9. 2017
- CD99 is a therapeutic target on disease stem cells in myeloid malignancies.. 9. 2017
- Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.. 9. 2017
- Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis.. 8. 2016
- Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas.. 8. 2016
- Maternal HIV infection influences the microbiome of HIV-uninfected infants.. 8. 2016
- P-selectin is a nanotherapeutic delivery target in the tumor microenvironment.. 8. 2016
- Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.. 8. 2016
- Somatic PIK3CA mutations as a driver of sporadic venous malformations.. 8. 2016
- Targeted fibrillar nanocarbon RNAi treatment of acute kidney injury.. 8. 2016
- Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment.. 8. 2016
- Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.. 8. 2016
- TLR-7 activation enhances IL-22-mediated colonization resistance against vancomycin-resistant enterococcus.. 8. 2016
- CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.. 8. 2016
- Immune history profoundly affects broadly protective B cell responses to influenza.. 7. 2015
- Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle.. 7. 2015
- Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer.. 7. 2015
- TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL.. 7. 2015
- A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo.. 7. 2015
- Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.. 7. 2015
- Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.. 7. 2015
- PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer.. 7. 2015
- Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window.. 7. 2015
- Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo.. 7. 2015
- Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.. 7. 2015
- Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep.. 6. 2014
- Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity.. 6. 2014
- Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin.. 6. 2014
- Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe.. 6. 2014
- Broadly neutralizing antibodies abrogate established hepatitis C virus infection.. 6. 2014
- Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia.. 6. 2014
- Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.. 6. 2014
- Pituitary expression of CTLA-4 mediates hypophysitis secondary to administration of CTLA-4 blocking antibody.. 6. 2014
- Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy.. 6. 2014
- Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia.. 6. 2014
- Structural, biochemical, and clinical characterization of epidermal growth factor receptor (EGFR) exon 20 insertion mutations in lung cancer.. 5. 2013
- PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses.. 5. 2013
- Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR.. 5. 2013
- Sclerostin inhibition reverses skeletal fragility in an Lrp5-deficient mouse model of OPPG syndrome.. 5. 2013
- mTORC1 inhibition is required for sensitivity to PI3K p110α inhibitors in PIK3CA-mutant breast cancer.. 5. 2013
- An integrated clinico-metabolomic model improves prediction of death in sepsis.. 5. 2013
- Impaired sphingolipid synthesis in the respiratory tract induces airway hyperreactivity.. 5. 2013
- CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia.. 5. 2013
- Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination.. 5. 2013
- Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.. 5. 2013
- Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans.. 5. 2013
- Lineage structure of the human antibody repertoire in response to influenza vaccination.. 5. 2013
- TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation.. 5. 2013
- Pazopanib enhances paclitaxel-induced mitotic catastrophe in anaplastic thyroid cancer.. 5. 2013
- Human melanoma metastasis in NSG mice correlates with clinical outcome in patients.. 4. 2012
- Proteasome inhibition alleviates SNARE-dependent neurodegeneration.. 4. 2012
- Cardiac glycosides exert anticancer effects by inducing immunogenic cell death.. 4. 2012
- AAV-directed persistent expression of a gene encoding anti-nicotine antibody for smoking cessation.. 4. 2012
- Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile.. 4. 2012
- Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses.. 4. 2012
- Notch4 normalization reduces blood vessel size in arteriovenous malformations.. 4. 2012
- Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma.. 4. 2012
- Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration.. 3. 2011
- Preclinical and clinical evaluation of intraductally administered agents in early breast cancer.. 3. 2011
- A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms.. 3. 2011
- Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma.. 3. 2011
- Biomedical innovation: a risky business at risk.. 3. 2011
- Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling.. 3. 2011
- A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma.. 3. 2011
- In vivo liver regeneration potential of human induced pluripotent stem cells from diverse origins.. 3. 2011
- Electronic medical records for genetic research: results of the eMERGE consortium.. 3. 2011
- Breast cancer methylomes establish an epigenomic foundation for metastasis.. 3. 2011
- Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus.. 3. 2011
- TLR9 differentiates rapidly from slowly progressing forms of idiopathic pulmonary fibrosis.. 2. 2010
- Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens.. 2. 2010
- Frequent release of low amounts of herpes simplex virus from neurons: results of a mathematical model.. 1. 2009
- Synthetic lethality and beyond.. 8. 2016
- Making waves in consciousness research.. 5. 2013
- Antisense gets a grip on miR-122 in chimpanzees.. 2. 2010
- Comment on "ALK is a therapeutic target for lethal sepsis". 2018
- Treg cells in cancer: a case of multiple personality disorder. 2012
- Comment on "the predictive capacity of personal genome sequencing". 2012
- Biology of antimicrobial resistance and approaches to combat it. 2020
- The hallmarks of successful anticancer immunotherapy. 2018
- Imaging approaches to optimize molecular therapies. 2016
- On being less tolerant: enhanced cancer immunosurveillance enabled by targeting checkpoints and agonists of T cell activation. 2015
- Fresh approaches to anti-infective therapies. 2012
- Fusion peptide-directed antibodies: Humoral armor against HIV-1 infection. 2024
- Cancer metabolism gets physical. 2018