European journal of medicinal chemistry Journal

Overview

publication venue for

Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity.. 269. 2024
Multicomponent Petasis reaction for the identification of pyrazine based multi-target directed anti-Alzheimer's agents: In-silico design, synthesis, and characterization.. 254. 2023
Synthesis and evaluation of 7-(3-aminopropyloxy)-substituted flavone analogue as a topoisomerase IIα catalytic inhibitor and its sensitizing effect to enzalutamide in castration-resistant prostate cancer cells.. 246. 2022
Identification of new halogen-containing 2,4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase inhibitors.. 227. 2021
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects.. 227. 2021
Discovery of a 2,4-diphenyl-5,6-dihydrobenzo(h)quinolin-8-amine derivative as a novel DNA intercalating topoisomerase IIα poison.. 226. 2021
Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation.. 215. 2021
Exploration of novel macrocyclic dipeptide N-benzyl amides as proteasome inhibitors.. 164. 2018
Design, synthesis, and biological evaluation of novel phenol ether derivatives as non-covalent proteasome inhibitors.. 161. 2018
Synthesis and biological effect of chrom-4-one derivatives as functional inhibitors of heat shock protein 27.. 139. 2017
Isatin-β-thiocarbohydrazones: Microwave-assisted synthesis, antitumor activity and structure-activity relationship.. 128. 2017
Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography.. 104. 2015
Preliminary research on 1-(4-bromo-2-nitroimidazol-1-yl)-3-[(18)F]fluoropropan-2-ol as a novel brain hypoxia PET tracer in a rodent model of stroke.. 101. 2015
Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.. 92. 2014
Synthesis and evaluation of (18)F-labeled ATP competitive inhibitors of topoisomerase II as probes for imaging topoisomerase II expression.. 86. 2014
Synthesis and in vitro antitumor activity of new series of benzothiazole and pyrimido[2,1-b]benzothiazole derivatives.. 85. 2014
N-(4-[(18)F]-fluoropyridin-2-yl)-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}carboxamides as analogs of WAY100635. New PET tracers of serotonin 5-HT(1A) receptors.. 85. 2014
Benzimidazole-based compounds kill Mycobacterium tuberculosis.. 75. 2014
Integrating docking scores, interaction profiles and molecular descriptors to improve the accuracy of molecular docking: toward the discovery of novel Akt1 inhibitors.. 75. 2014
Synthesis and antiproliferative action of a novel series of maprotiline analogues.. 71. 2013
Thiazole-aminopiperidine hybrid analogues: design and synthesis of novel Mycobacterium tuberculosis GyrB inhibitors.. 70. 2013
(99m)Tc-labeled dibenzylideneacetone derivatives as potential SPECT probes for in vivo imaging of β-amyloid plaque.. 64. 2013
¹⁸F-labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques.. 57. 2012
Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities.. 54. 2012
From COX-2 inhibitor nimesulide to potent anti-cancer agent: synthesis, in vitro, in vivo and pharmacokinetic evaluation.. 47. 2011
Cytotoxic oxasqualenoids from the red alga Laurencia viridis.. 46. 2011
Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.. 44. 2009
Classification models for CYP450 3A4 inhibitors and non-inhibitors.. 44. 2008
Radiolabeled bioactive benzoheterocycles for imaging β-amyloid plaques in Alzheimer's disease. 2014

Identity

ISO Abbreviation

Eur J Med Chem

Linking ISSN

0223-5234

Electronic International Standard Serial Number (EISSN)

1768-3254