Bioorganic chemistry
Journal
Overview
publication venue for
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Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents..
130.
2022
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Cytotoxicity, crosslinking and biological activity of three mitomycins..
123.
2022
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4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships..
116.
2021
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Dual targeting of acetylcholinesterase and tau aggregation: Design, synthesis and evaluation of multifunctional deoxyvasicinone analogues for Alzheimer's disease..
116.
2021
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Synthesis of benzoxazole-based vorinostat analogs and their antiproliferative activity..
114.
2021
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Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics..
109.
2021
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Computational drug discovery and repurposing for the treatment of COVID-19: A systematic review..
106.
2020
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Synthesis and evaluation of resveratrol derivatives as fetal hemoglobin inducers..
100.
2020
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New series of fused pyrazolopyridines: Synthesis, molecular modeling, antimicrobial, antiquorum-sensing and antitumor activities..
92.
2019
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Synthesis, molecular modeling and biological evaluation of new pyrazolo[3,4-b]pyridine analogs as potential antimicrobial, antiquorum-sensing and anticancer agents..
89.
2019
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Synthesis of TPEN variants to improve cancer cells selective killing capacity..
87.
2019
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Design and synthesis of donepezil analogues as dual AChE and BACE-1 inhibitors..
80.
2018
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Evaluation of 4-thiazolidinone derivatives as potential reverse transcriptase inhibitors against HIV-1 drug resistant strains..
71.
2017
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Chemoenzymatic synthesis of (S)-duloxetine using carbonyl reductase from Rhodosporidium toruloides..
65.
2016
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Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: Exploiting the "glass transition" in protein dynamics..
34.
2006
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S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used?
2011
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