publication venue for
- Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055.. 15. 2024
- Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.. 14. 2023
- Discovery of First-in-Class Small Molecule Inhibitors of Lymphocyte Activation Gene 3 (LAG-3).. 14. 2023
- A Chemical Strategy toward Novel Brain-Penetrant EZH2 Inhibitors.. 13. 2022
- Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10).. 12. 2021
- Quinoline-Pyrazole Scaffold as a Novel Ligand of Galectin-3 and Suppressor of TREM2 Signaling.. 11. 2020
- Brain Permeable Tafamidis Amide Analogs for Stabilizing TTR and Reducing APP Cleavage.. 11. 2020
- Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma.. 11. 2020
- Development of Kinase Inactive PD173955 Analogues for Reducing Production of Aβ Peptides.. 10. 2019
- New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons.. 9. 2018
- Target-Directed Self-Assembly of Homodimeric Drugs Against β-Tryptase.. 9. 2018
- Conformationally Constrained Cinnolinone Nucleoside Analogues as Siderophore Biosynthesis Inhibitors for Tuberculosis.. 9. 2018
- Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.. 9. 2018
- 18F-Radiolabeled Panobinostat Allows for Positron Emission Tomography Guided Delivery of a Histone Deacetylase Inhibitor.. 9. 2018
- Oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad spectrum antibacterial agents.. 5. 2014
- Oxathiazolones Selectively Inhibit the Human Immunoproteasome over the Constitutive Proteasome.. 5. 2014
- Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor.. 5. 2014
- Bisubstrate Inhibitors of Biotin Protein Ligase in Mycobacterium tuberculosis Resistant to Cyclonucleoside Formation.. 4. 2013
- Design, synthesis, and evaluation of prodrugs of ertapenem.. 4. 2013
- Triazole Appending Agent (TAAG): A New Synthon for Preparing Iodine-Based Molecular Imaging and Radiotherapy Agents.. 3. 2012
- Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis.. 2. 2011