Molecular cancer research : MCR
Journal
Overview
publication venue for
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A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients.
2021
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Tumor Cholesterol Synthesis, Statin Use, and Lethal Prostate Cancer.
2025
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Exome sequencing reveals a sparse genomic landscape in Kaposi sarcoma.
2025
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Expanding Our Horizon to Inform Cutting Edge Mechanistic Studies: Cancer Research Resources..
22.
2024
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Characterization of Wnt Signaling Pathway Aberrations in Metastatic Prostate Cancer..
22.
2024
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Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images.
2024
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Impact of Rare and Multiple Concurrent Gene Fusions on Diagnostic DNA Methylation Classifier in Brain Tumors..
22.
2024
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Overlaid Transcriptional and Proteome Analyses Identify Mitotic Kinesins as Important Targets of Arylsulfonamide-Mediated RBM39 Degradation..
21.
2023
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Significance of RB Loss in Unlocking Phenotypic Plasticity in Advanced Cancers..
21.
2023
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Activation of the JAK/STAT Pathway Leads to BRAF Inhibitor Resistance in BRAFV600E Positive Thyroid Carcinoma.
2023
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The prostate stromal transcriptome in aggressive and lethal prostate cancer.
2022
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Transcriptomes of prostate cancer with TMPRSS2:ERG and other ETS fusions.
2022
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Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer..
20.
2022
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Building tools for machine learning and artificial intelligence in cancer research: best practices and a case study with the PathML toolkit for computational pathology.
2021
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Genomic and Transcriptomic Correlates of Thyroid Carcinoma Evolution after BRAF Inhibitor Therapy..
20.
2021
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Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance..
19.
2021
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p53 Frameshift Mutations Couple Loss-of-Function with Unique Neomorphic Activities..
19.
2021
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High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab..
19.
2021
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Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer..
19.
2021
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Circulating Tumor Cell Genomic Evolution and Hormone Therapy Outcomes in Men with Metastatic Castration-Resistant Prostate Cancer..
19.
2021
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Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor..
19.
2021
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AKT1 E17K Inhibits Cancer Cell Migration by Abrogating β-Catenin Signaling..
19.
2020
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Metabolomics of Prostate Cancer Gleason Score in Tumor Tissue and Serum..
19.
2020
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Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9..
18.
2020
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Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival..
18.
2020
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Cdc42 Mediates Cancer Cell Chemotaxis in Perineural Invasion..
18.
2020
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Combination Lenalidomide/Bortezomib Treatment Synergistically Induces Calpain-Dependent Ikaros Cleavage and Apoptosis in Myeloma Cells..
18.
2020
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Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis..
18.
2019
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Distinct Roles for BET Family Members in Estrogen Receptor α Enhancer Function and Gene Regulation in Breast Cancer Cells..
17.
2019
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Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells..
17.
2019
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MCL1 and DEDD Promote Urothelial Carcinoma Progression..
17.
2019
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Molecular Characterization of Prostate Cancer with Associated Gleason Score Using Mass Spectrometry Imaging..
17.
2019
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Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma..
17.
2019
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Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells.
17:1365-1377.
2019
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PDCD4 Is an Androgen-Repressed Tumor Suppressor that Regulates Prostate Cancer Growth and Castration Resistance..
17.
2018
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Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate..
17.
2018
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Impeding Circulating Tumor Cell Reseeding Decelerates Metastatic Progression and Potentiates Chemotherapy..
16.
2018
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Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma..
16.
2018
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Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma..
16.
2018
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Cancer Stem Cell Phenotypes in ER+ Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes..
16.
2018
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Targeted AKT Inhibition in Prostate Cancer Cells and Spheroids Reduces Aerobic Glycolysis and Generation of Hyperpolarized [1-13C] Lactate..
16.
2018
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A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer..
15.
2017
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Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation..
15.
2017
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Chromosome 20q Amplification Defines a Subtype of Microsatellite Stable, Left-Sided Colon Cancers with Wild-type RAS/RAF and Better Overall Survival..
15.
2017
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Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues..
15.
2017
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Pathology-Driven Comprehensive Proteomic Profiling of the Prostate Cancer Tumor Microenvironment..
15.
2017
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High-Fat Diet-Induced Complement Activation Mediates Intestinal Inflammation and Neoplasia, Independent of Obesity..
14.
2016
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Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF..
14.
2015
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Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma..
14.
2015
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Defining ATM-Independent Functions of the Mre11 Complex with a Novel Mouse Model..
14.
2015
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Measuring PI3K Activation: Clinicopathologic, Immunohistochemical, and RNA Expression Analysis in Prostate Cancer..
13.
2015
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The Role of Nitric Oxide Synthase Uncoupling in Tumor Progression..
13.
2015
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Genome-Wide Profiling of TRACK Kidneys Shows Similarity to the Human ccRCC Transcriptome..
13.
2015
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AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants..
13.
2015
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The chemokine (CCL2-CCR2) signaling axis mediates perineural invasion..
13.
2014
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p53 Promotes cell survival due to the reversibility of its cell-cycle checkpoints..
13.
2014
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Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors..
12.
2014
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Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans..
12.
2014
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Prostate cancer genetic-susceptibility locus on chromosome 20q13 is amplified and coupled to androgen receptor-regulation in metastatic tumors..
12.
2013
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The twist box domain is required for Twist1-induced prostate cancer metastasis..
11.
2013
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Metabolic alterations in lung cancer-associated fibroblasts correlated with increased glycolytic metabolism of the tumor..
11.
2013
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Alpha-CaMKII plays a critical role in determining the aggressive behavior of human osteosarcoma..
11.
2013
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Diminished origin-licensing capacity specifically sensitizes tumor cells to replication stress..
11.
2013
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Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer..
11.
2013
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Notch signaling contributes to lung cancer clonogenic capacity in vitro but may be circumvented in tumorigenesis in vivo..
9.
2011
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Imatinib upregulates compensatory integrin signaling in a mouse model of gastrointestinal stromal tumor and is more effective when combined with dasatinib..
8.
2010
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Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer..
7.
2009
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Calcineurin a-binding protein, a novel modulator of the calcineurin-nuclear factor of activated T-cell signaling pathway, is overexpressed in wilms' tumors and promotes cell migration..
7.
2009
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Rembrandt: helping personalized medicine become a reality through integrative translational research..
7.
2009
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MDM2 gene amplification is correlated to tumor progression but not to the presence of SNP309 or TP53 mutational status in primary colorectal cancers..
6.
2008
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Genomic changes and gene expression profiles reveal that established glioma cell lines are poorly representative of primary human gliomas..
6.
2008
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Acquisition of stable inducible up-regulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells..
6.
2008
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Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation..
6.
2008
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Lysophosphatidic acid down-regulates stress fibers and up-regulates pro-matrix metalloproteinase-2 activation in ovarian cancer cells..
5.
2007
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Inhibition of matrilysin expression by antisense or RNA interference decreases lysophosphatidic acid-induced epithelial ovarian cancer invasion..
4.
2006
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Epithelial-restricted gene profile of primary cultures from human prostate tumors: a molecular approach to predict clinical behavior of prostate cancer..
4.
2006
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Mammalian target of rapamycin promotes vincristine resistance through multiple mechanisms independent of maintained glycolytic rate..
3.
2005
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Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types..
2.
2004
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Fatty acid synthase expression defines distinct molecular signatures in prostate cancer..
1.
2003
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Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein..
1.
2003
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Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarcinoma cells..
1.
2003
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Direct evidence that Bcr-Abl tyrosine kinase activity disrupts normal synergistic interactions between Kit ligand and cytokines in primary primitive progenitor cells..
1.
2003
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Dissecting the Dual Role of AMPK in Cancer: From Experimental to Human Studies.
2015
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Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes.
2018
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The N-myc Oncogene: Maximizing its Targets, Regulation, and Therapeutic Potential.
2014
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