Neuropharmacology

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L-type calcium channel regulation of depression, anxiety and anhedonia-related behavioral phenotypes following chronic stress exposure.. 257. 2024
Click-train evoked steady state harmonic response as a novel pharmacodynamic biomarker of cortical oscillatory synchrony.. 240. 2023
Volatile anesthetics inhibit presynaptic cGMP signaling to depress presynaptic excitability in rat hippocampal neurons.. 240. 2023
Circuit and neuropeptide mechanisms of the paraventricular thalamus across stages of alcohol and drug use. 198. 2021
Neuroendocrine response to GABA-B receptor agonism in alcohol-dependent individuals: Results from a combined outpatient and human laboratory experiment.. 137. 2018
DPI-289, a novel mixed delta opioid agonist / mu opioid antagonist (DAMA), has L-DOPA-sparing potential in Parkinson's disease.. 131. 2017
The BDNF Val66Met polymorphism enhances glutamatergic transmission but diminishes activity-dependent synaptic plasticity in the dorsolateral striatum.. 112. 2016
Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala.. 99. 2015
Restoration of cocaine stimulation and reward by reintroducing wild type dopamine transporter in adult knock-in mice with a cocaine-insensitive dopamine transporter.. 86. 2014
Glutamatergic mechanisms associated with stress-induced amygdala excitability and anxiety-related behavior.. 85. 2014
Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.. 79. 2014
Behavior of knock-in mice with a cocaine-insensitive dopamine transporter after virogenetic restoration of cocaine sensitivity in the striatum.. 79. 2014
Objective and subjective cognitive enhancing effects of mixed amphetamine salts in healthy people.. 64. 2012
The rewarding and locomotor-sensitizing effects of repeated cocaine administration are distinct and separable in mice.. 62. 2011
Chronic stress alters neuropeptide Y signaling in the bed nucleus of the stria terminalis in DBA/2J but not C57BL/6J mice.. 62. 2011
Regional differences in the effects of isoflurane on neurotransmitter release.. 61. 2011
The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents.. 61. 2011
Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments.. 61. 2011
Differential glutamate AMPA-receptor plasticity in subpopulations of VTA neurons in the presence or absence of residual cocaine: implications for the development of addiction.. 61. 2011
Prenatal L-DOPA exposure produces lasting changes in brain dopamine content, cocaine-induced dopamine release and cocaine conditioned place preference.. 60. 2010
The binding sites for benztropines and dopamine in the dopamine transporter overlap.. 60. 2010
Serotonin(1A)-receptor-dependent signaling proteins in mouse hippocampus.. 57. 2009
Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms.. 56. 2008
Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation.. 56 Suppl 1. 2008
General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.. 53. 2007
Intracellular cholesterol changes induced by translocator protein (18 kDa) TSPO/PBR ligands.. 53. 2007
A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.. 49. 2005
Munc18-dependent regulation of synaptic vesicle exocytosis by syntaxin-1A in hippocampal neurons.. 48. 2005
Sodium channel blocking activity of AM-36 and sipatrigine (BW619C89): in vitro and in vivo evidence.. 47. 2004
Excitotoxic profiles of novel, low-affinity kainate receptor agonists in primary cultures of murine cerebellar granule cells.. 41. 2001
Group II mGlu receptor agonists fail to protect against various neurotoxic insults induced in murine cortical, striatal and cerebellar granular pure neuronal cultures.. 41. 2001
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia.. 39. 2000
Role of sensory deficits in motor impairments after injury to primary motor cortex.. 39. 2000
CHEB, a convulsant barbiturate, evokes calcium-dependent spontaneous glutamate release from rat cerebrocortical synaptosomes.. 35. 1996
Nitric oxide and adenosine mediate vasodilation during functional activation in cerebellar cortex.. 33. 1994
Nitric oxide and opioid tolerance.. 33. 1994
Effect of acute and chronic administration of buspirone on serotonin and benzodiazepine receptor subtypes in the rat brain: an autoradiographic study.. 30. 1991
Selective inhibition of nociceptive flexion reflex discharge by the kappa agonist bremazocine.. 26. 1987
Potentiation by cocaine of the stimulus-induced increase in dopamine synthesis in rat brain striatal synaptosomes.. 16. 1977
The effect of LSD upon sponstaneous PGO wave activity and REM sleep in the cat.. 14. 1975
An analysis of the effect of reserpine upon ponto-geniculo-ooccipital wave activity in the cat.. 11. 1972
Brain stem serotonin depletion and ponto-geniculo-occipital wave activity in the cat treated with reserpine.. 11. 1972
A symphony of signals conducts early and late stages of adult neurogenesis. 2010
Circuit and neuropeptide mechanisms of the paraventricular thalamus across stages of alcohol and drug use. 2021
The role of DNA methylation in stress-related psychiatric disorders. 2014

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Neuropharmacology Journal

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