Journal of molecular biology

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Membrane binding induces distinct structural signatures in the mouse complexin-1 C-terminal domain. 2022
Structural Mechanics of the Alpha-2-Macroglobulin Transformation.. 434. 2021
Molecular Determinants in tRNA D-arm Required for Inhibition of HIV-1 Gag Membrane Binding.. 434. 2021
The piggyBac-derived protein 5 (PGBD5) transposes both the closely and the distantly related piggyBac-like elements Tcr-pble and Ifp2.. 433. 2021
The C-terminal Domain of piggyBac Transposase Is Not Required for DNA Transposition.. 433. 2021
Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus.. 432. 2020
Elongation Factor Tu Switch I Element is a Gate for Aminoacyl-tRNA Selection.. 432. 2020
CD8 Binding of MHC-Peptide Complexes in cis or trans Regulates CD8⁺ T-cell Responses.. 431. 2019
CARM1 (PRMT4) Acts as a Transcriptional Coactivator during Retinoic Acid-Induced Embryonic Stem Cell Differentiation.. 430. 2018
Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor.. 430. 2018
G-Protein Gα₁₃ Functions with Abl Kinase to Regulate Actin Cytoskeletal Reorganization.. 429. 2017
Real-time Visualization of Phospholipid Degradation by Outer Membrane Phospholipase A using High-Speed Atomic Force Microscopy.. 429. 2017
Structure of a TCR-Mimic Antibody with Target Predicts Pharmacogenetics.. 428. 2015
Sequence and membrane determinants of the random coil-helix transition of α-synuclein.. 426. 2014
The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions.. 425. 2013
77Se enrichment of proteins expands the biological NMR toolbox. 425:222-231. 2013
High-speed atomic force microscopy: cooperative adhesion and dynamic equilibrium of junctional microdomain membrane proteins.. 423. 2012
Crystal structure and regulation mechanisms of the CyaB adenylyl cyclase from the human pathogen Pseudomonas aeruginosa.. 416. 2011
Two-dimensional kinetics of inter-connexin interactions from single-molecule force spectroscopy.. 412. 2011
PDZ binding to the BAR domain of PICK1 is elucidated by coarse-grained molecular dynamics.. 405. 2010
Temporal regulation of gene expression of the Thermus thermophilus bacteriophage P23-45.. 405. 2010
Conformational sampling of aminoacyl-tRNA during selection on the bacterial ribosome.. 399. 2010
Molecular and structural insight into proNGF engagement of p75NTR and sortilin.. 396. 2009
Quinone pathways in entire photosynthetic chromatophores of Rhodospirillum photometricum.. 393. 2009
E46K Parkinson's-linked mutation enhances C-terminal-to-N-terminal contacts in alpha-synuclein.. 388. 2009
Structure and activity of human mitochondrial peptide deformylase, a novel cancer target.. 387. 2009
Active transcription is required for maintenance of epigenetic memory in the malaria parasite Plasmodium falciparum.. 382. 2008
Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cells.. 377. 2008
Genomic and proteomic analysis of phiEco32, a novel Escherichia coli bacteriophage.. 377. 2008
Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways.. 377. 2007
Direct visualization of KirBac3.1 potassium channel gating by atomic force microscopy.. 374. 2007
Residual structure, backbone dynamics, and interactions within the synuclein family.. 372. 2007
Crystal structure of the Escherichia coli regulator of sigma70, Rsd, in complex with sigma70 domain 4.. 372. 2007
Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells.. 372. 2007
Ligand binding and activation in a prokaryotic cyclic nucleotide-modulated channel.. 371. 2007
Supramolecular assembly of VDAC in native mitochondrial outer membranes.. 369. 2007
Increasing protein conformational stability by optimizing beta-turn sequence. 373:211-218. 2007
Synergism between halide binding and proton transport in a CLC-type exchanger.. 362. 2006
Folding of the repeat domain of tau upon binding to lipid surfaces.. 362. 2006
The photosynthetic apparatus of Rhodopseudomonas palustris: structures and organization.. 358. 2006
Multiple solvent crystal structures: probing binding sites, plasticity and hydration.. 357. 2006
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein.. 356. 2005
The atomic resolution crystal structure of the YajL (ThiJ) protein from Escherichia coli: a close prokaryotic homologue of the Parkinsonism-associated protein DJ-1.. 353. 2005
The 4.5 A structure of human AQP2.. 350. 2005
Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2.. 349. 2005
Specific contributions of histone tails and their acetylation to the mechanical stability of nucleosomes.. 346. 2004
Sequence-dependent kinetic model for transcription elongation by RNA polymerase.. 344. 2004
3DCoffee: combining protein sequences and structures within multiple sequence alignments.. 340. 2004
Molecular dynamics simulations of transducin: interdomain and front to back communication in activation and nucleotide exchange.. 338. 2004
Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine.. 337. 2004
Studies of the Escherichia coli Rsd-sigma70 complex.. 335. 2004
A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy.. 332. 2003
A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins.. 329. 2003
Crystal structure of MHC class II I-Ab in complex with a human CLIP peptide: prediction of an I-Ab peptide-binding motif.. 326. 2003
AFM characterization of tilt and intrinsic flexibility of Rhodobacter sphaeroides light harvesting complex 2 (LH2).. 325. 2003
Structural mimicry of proline kinks: tertiary packing interactions support local structural distortions.. 318. 2002
Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs.. 312. 2001
The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E.. 312. 2001
V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads.. 311. 2001
A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple.. 310. 2001
Conformational properties of alpha-synuclein in its free and lipid-associated states.. 307. 2001
The DNA-binding domain in the Bacillus subtilis transition-state regulator AbrB employs significant motion for promiscuous DNA recognition.. 305. 2001
A detailed interpretation of OH radical footprints in a TBP-DNA complex reveals the role of dynamics in the mechanism of sequence-specific binding.. 304. 2000
The aquaporin sidedness revisited.. 299. 2000
Characterization of millisecond time-scale dynamics in the molten globule state of alpha-lactalbumin by NMR.. 294. 1999
Universal DNA microarray method for multiplex detection of low abundance point mutations.. 292. 1999
Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis.. 289. 1999
Temperature dependence of intramolecular dynamics of the basic leucine zipper of GCN4: implications for the entropy of association with DNA.. 285. 1999
Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.. 285. 1999
Conformational changes of the Tet repressor induced by tetracycline trapping.. 279. 1998
The structural stability of the co-chaperonin GroES.. 272. 1997
Dynamic interplay of TFIIA, TBP and TATA DNA.. 271. 1997
Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries.. 267. 1997
Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus.. 266. 1997
Is apomyoglobin a molten globule? Structural characterization by NMR.. 263. 1996
RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide.. 262. 1996
Intramolecular transmission of the ATP regulatory signal in Escherichia coli aspartate transcarbamylase: specific involvement of a clustered set of amino acid interactions at an interface between regulatory and catalytic subunits.. 246. 1995
Crystallization and preliminary X-ray studies of the diphtheria Tox repressor from Corynebacterium diphtheriae.. 244. 1994
Expression, crystallization and preliminary crystallographic analysis of human carbonyl reductase.. 244. 1994
The activation of Escherichia coli aspartate transcarbamylase by ATP. Specific involvement of helix H2' at the hydrophobic interface between the two domains of the regulatory chains.. 242. 1994
Analysis of two-residue turns in proteins.. 238. 1994
Energetics of heterodimer formation among gramicidin analogues with an NH2-terminal addition or deletion. Consequences of missing a residue at the join in the channel.. 231. 1993
Crystallization and preliminary crystallographic analysis of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli.. 228. 1992
Heterotropic interactions in Escherichia coli aspartate transcarbamylase. Subunit interfaces involved in CTP inhibition and ATP activation.. 220. 1991
Co-operative interactions between the catalytic sites in Escherichia coli aspartate transcarbamylase. Role of the C-terminal region of the regulatory chains.. 216. 1990
Location of nucleosomes in simian virus 40 chromatin.. 214. 1990
Establishment of de novo DNA methylation patterns. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter.. 214. 1990
Energetics of gramicidin hybrid channel formation as a test for structural equivalence. Side-chain substitutions in the native sequence.. 211. 1990
Locations of nucleosomes on the regulatory region of simian virus 40 chromatin.. 210. 1989
Genomic organization of the glyceraldehyde-3-phosphate dehydrogenase gene family of Caenorhabditis elegans.. 206. 1989
Extent of duplex DNA underwinding induced by RecA protein binding in the presence of ATP.. 205. 1989
Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast.. 204. 1988
General mechanism for RecA protein binding to duplex DNA.. 203. 1988
A promoter of the rat insulin-like growth factor II gene consists of minimal control elements.. 199. 1988
Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences.. 198. 1987
Preliminary X-ray data for a D-amino acid amino-transferase from a novel thermophilic Bacillus.. 196. 1987
X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution.. 192. 1986
Effect of anisotropy and anharmonicity on protein crystallographic refinement. An evaluation by molecular dynamics.. 190. 1986
Partial nucleotide sequence of the Murray Valley encephalitis virus genome. Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins.. 187. 1986
Structure-function relationship in allosteric aspartate carbamoyltransferase from Escherichia coli. II. Involvement of the C-terminal region of the regulatory chain in homotropic and heterotropic interactions.. 186. 1985
Analysis of the metal-induced conformational change in myosin with a monoclonal antibody to light chain two.. 183. 1985
Extrachromosomal DNA forms of copia-like transposable elements, F elements and middle repetitive DNA sequences in Drosophila melanogaster. Variation in cultured cells and embryos.. 182. 1985
Recombinant DNA approach for defining the primary structure of monoclonal antibody epitopes. The analysis of a conformation-specific antibody to myosin light chain 2.. 181. 1985
Structure of oxidized flavodoxin from Anacystis nidulans.. 165. 1983
Crystallization of the Fab fragment of a monoclonal anti-digoxin antibody and its complex with digoxin.. 165. 1983
Three-dimensional structure of orthorhombic purple membrane at 6.5 A resolution.. 163. 1983
Preliminary X-ray data for the ribose binding protein from Salmonella typhimurium.. 160. 1982
Association of sindbis virion glycoproteins and their precursors.. 154. 1982
Isolation and characterization of the hydrophobic COOH-terminal domains of the sindbis virion glycoproteins.. 154. 1982
Synthesis, cleavage and sequence analysis of DNA complementary to the 26 S messenger RNA of Sindbis virus.. 150. 1981
Preliminary x-ray data for the galactose binding protein from Salmonella typhimurium.. 147. 1981
Structure of viral DNA and RNA in mammalian cells infected with avian sarcoma virus.. 143. 1980
Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage lambda receptor.. 141. 1980
N-6-methyl-adenosine in adenovirus type 2 nuclear RNA is conserved in the formation of messenger RNA.. 135. 1979
On the protein crystal chemistry of chloroplatinite ions: general principles and interactions with triose phosphate isomerase.. 120. 1978
Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells.. 120. 1978
Uptake of homologous single-stranded fragments by superhelical DNA. III. The product and its enzymic conversion to a recombinant molecule.. 116. 1977
Uptake of homologous single-stranded fragments by superhelical DNA. IV. Branch migration.. 116. 1977
Comparison of mouse mammary tumor virus-specific DNA in inbred, wild and Asian mice, and in tumors and normal organs from inbred mice.. 114. 1977
Covalently closed circular DNA of avian sarcoma virus: purification from nuclei of infected quail tumor cells and measurement by electron microscopy and gel electrophoresis.. 106. 1976
The structure of subtilopeptidase A. I. X-ray crystallographic data.. 106. 1976
The induction of protein X in DNA repair and cell division mutants of Escherichia coli.. 104. 1976
DNA synthesis inhibition and the induction of protein X in Escherichia coli.. 101. 1976
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses.. 101. 1976
Protein crystallography at sub-zero temperatures: cryo-protective mother liquors for protein crystals.. 96. 1975
Protein crystallography at sub-zero temperatures: lysozyme-substrate complexes in cooled mixed solvents.. 96. 1975
Letter: Evidence for non-repetitive subunits in the genome of Rous sarcoma virus.. 84. 1974
Transcription of mouse mammary tumor virus genes in tissues from high and low tumor incidence mouse strains.. 79. 1973
Appearance of virus-specific DNA in mammalian cells following transformation by Rous sarcoma virus.. 74. 1973
MULTIPLE MOLECULAR FORMS OF BETA-GALACTOSIDASE.. 11. 1965
The mysterious C-terminal tail of alpha-synuclein: nanobody's guess.. 425. 2013
Molecular Highways-Navigating Collisions of DNA Motor Proteins. 2018
Cell Cycle Control by PTEN. 2017
Regulation, Signaling, and Physiological Functions of G-Proteins. 2016
TMEM16 proteins: unknown structure and confusing functions. 2014
Complexin membrane interactions: implications for synapse evolution and function. 2022
What do Transcription Factors Interact With? 2021
Menacing Mold: Recent Advances in Aspergillus Pathogenesis and Host Defense. 2019
Molecular details of cAMP generation in mammalian cells: a tale of two systems. 2006

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