publication venue for
- Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome. 2024
- A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis. 2023
- Highly efficient cellular expression of circular mRNA enables prolonged protein expression. 2023
- Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance. 2023
- Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. 2023
- In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system. 2022
- Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer.. 29. 2021
- Naturally occurring three-way junctions can be repurposed as genetically encoded RNA-based sensors. 2021
- A fine-tuned azobenzene for enhanced photopharmacology in vivo. 2021
- A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death.. 28. 2021
- A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization.. 26. 2019
- Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β.. 26. 2019
- A Chemical Strategy for Protease Substrate Profiling.. 26. 2019
- Detection of Low-Abundance Metabolites in Live Cells Using an RNA Integrator.. 26. 2019
- Modulating Protein-Protein Interactions of the Mitotic Polo-like Kinases to Target Mutant KRAS.. 24. 2017
- Deacylation Mechanism by SIRT2 Revealed in the 1'-SH-2'-O-Myristoyl Intermediate Structure.. 24. 2017
- Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis.. 24. 2017
- Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.. 24. 2016
- A Data-Driven Approach to Predicting Successes and Failures of Clinical Trials.. 23. 2016
- Fluorescent RNA Aptamers as a Tool to Study RNA-Modifying Enzymes.. 23. 2016
- Phenotypic technologies in stem cell biology. 2021
- The Chemical Biology of Ferroptosis in the Central Nervous System. 2020