Cancer biology & therapy

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NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma.. 24. 2023
NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction.. 22. 2021
Doxycycline-induced exogenous Bmi-1 expression enhances tumor formation in a murine model of oral squamous cell carcinoma.. 21. 2020
Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon cancer cells.. 17. 2016
Fibroblast activation protein protects bortezomib-induced apoptosis in multiple myeloma cells through β-catenin signaling pathway.. 15. 2014
Impact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib.. 15. 2014
Alterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells.. 14. 2013
Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models.. 12. 2011
Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts.. 12. 2011
Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer.. 11. 2011
Mesenchymal stem cells expressing GD2 and CD271 correlate with breast cancer-initiating cells in bone marrow.. 11. 2011
Triggering of toll-like receptor-4 in human multiple myeloma cells promotes proliferation and alters cell responses to immune and chemotherapy drug attack.. 11. 2011
Clinical and biological impact of EphA2 overexpression and angiogenesis in endometrial cancer.. 10. 2010
DNA methylation-related vitamin D receptor insensitivity in breast cancer.. 10. 2010
Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies.. 9. 2010
An allosteric Akt inhibitor effectively blocks Akt signaling and tumor growth with only transient effects on glucose and insulin levels in vivo.. 9. 2010
A translational end-run for a rare, genetically enigmatic tumor.. 8. 2009
Amplification of chromosomal segment 4q12 in non-small cell lung cancer.. 8. 2009
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells.. 8. 2009
Atrasentan (ABT-627) enhances perfusion and reduces hypoxia in a human tumor xenograft model.. 8. 2009
Anti-angiogenic properties of metronomic topotecan in ovarian carcinoma.. 8. 2009
Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen.. 8. 2009
Characterization CSMD1 in a large set of primary lung, head and neck, breast and skin cancer tissues.. 8. 2009
Fenugreek: a naturally occurring edible spice as an anticancer agent.. 8. 2009
PKCalpha activation downregulates ATM and radio-sensitizes androgen-sensitive human prostate cancer cells in vitro and in vivo.. 8. 2009
Gene microarray analysis of human renal cell carcinoma: the effects of HDAC inhibition and retinoid treatment.. 7. 2008
Downregulation of KSR1 in pancreatic cancer xenografts by antisense oligonucleotide correlates with tumor drug uptake.. 7. 2008
Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma.. 7. 2008
Reduced expression of PNUTS leads to activation of Rb-phosphatase and caspase-mediated apoptosis.. 7. 2008
Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression.. 6. 2007
Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients.. 6. 2007
Detecting changes in tumor hypoxia with carbonic anhydrase IX and pimonidazole.. 6. 2007
Intraperitoneal delivery of liposomal siRNA for therapy of advanced ovarian cancer.. 5. 2006
Analysis of EphA2 expression and mutant p53 in ovarian carcinoma.. 5. 2006
Circulating cell-free DNA: a novel biomarker for response to therapy in ovarian carcinoma.. 5. 2006
Dexamethasone decreases xenograft response to Paclitaxel through inhibition of tumor cell apoptosis.. 5. 2006
The role of relaxin in endometrial cancer.. 5. 2006
Cisplatin-induced GADD34 upregulation potentiates oncolytic viral therapy in the treatment of malignant pleural mesothelioma.. 5. 2006
Assessment of Epidermal Growth Factor Receptor (EGFR) signaling in paired colorectal cancer and normal colon tissue samples using computer-aided immunohistochemical analysis.. 4. 2005
Immortalizing the complexity of cancer metastasis: genetic features of lethal metastatic pancreatic cancer obtained from rapid autopsy.. 4. 2005
Overexpression of E2F-1 in lung and liver metastases of human colon cancer is associated with gene amplification.. 3. 2004
CD95 rapidly clusters in cells of diverse origins.. 2. 2003
Stem cells, differentiation and cancer: mentors, colleagues and academic administration.. 5. 2006
p53 family members: similar biochemistry, different biology.. 4. 2005
Reassessing the usual suspects causing a commotion in the blood (and vessels?).. 3. 2004
The biology of hormone refractory breast and prostate cancer: An NCI workshop report. 2009
FoxO family members in cancer. 2011
The molecular pathogenesis of small cell lung cancer. 2010
MLL fusions: pathways to leukemia. 2009
Exploitation of the HIF axis for cancer therapy. 2004
Wnt signaling and breast cancer. 2004
Biomarkers for ovarian cancer detection and therapy. 2010
An introduction to pancreatic adenocarcinoma genetics, pathology and therapy. 2002

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Cancer biology & therapy Journal

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