awards grant
- A three-dimensional tissue model linking tau tangles, abeta and microglial CD33-isoform state to gene- and isoform-expression dysregulation.
- A three-dimensional tissue model linking tau tangles, abeta and microglial CD33-isoform state to gene- and isoform-expression dysregulation.
- Biochemical and Functional Analysis of CSF and lymph following changes in brain fluid dynamics.
- Comparison of cell-autonomous and cell-non-autonomous effects of Aβ and tau aggregates and microglial CD33-isoforms between entorhinal cortex and hippocampus
- Hypertension, tau and neurodegeneration
- Identification and development of CD33 inhibitors and pre-RNA splicing modulators
- Microglial-astrocytic mechanisms of APOE3 Christchurch-mediated resilience to tauopathy
- Sex-biased TLR7 signaling in demyelination and its inhibition by small molecules
- Tau-induced postsynaptic dysfunction in tauopathy models