Brain and Mind Research
Academic Department
Research
administers grant
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18F-PU-AD epichaperome PET to characterize and diagnose AD and ADRD
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A Circuit Mechanism for the Development of Cortico-cortical Connectivity
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A clear view of encephalitis: a single cell approach to determine the basis of flaviviral pathogenesis in the central nervous system
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A novel gene therapy approach to prevent alpha-synuclein misfolding in multiple system atrophy
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Alzheimer Pathology and Neurovascular Dysfunction
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An in vivo strategy to study the impact of GABRB3 mutations on the development of cortical circuits
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ApoE4, neurovascular injury and cognitive impairment
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Assessment of early somatosensory impairment in the KIKO mouse model of Friedreich''s ataxia
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Astrocyte RNA degradation and cognitive function
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Astrocyte dysfunction in idiopathic autism
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Astrocytic function of the novel ASD-risk gene GIGYF1 in brain development
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BRAIN CONNECTS: The Center for Large-scale Imaging of Neural Circuits (LINC)
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Biopharma Agreement with Astoria Biologica
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CHCHD10 frontotemporal dementia, molecular mechanisms and therapeutic strategies
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CZI DAF
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Calcium communication among intracellular compartments in FA patient-derived cells
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Cell & non-cell autonomous effects of frataxin deficiency in FA pathophysiology
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Cell type atlasing of whole human brains using HOLiS: an optimized pipeline for staining, clearing, imaging, and analysis
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Cellular Mechanism of Adult Onset Neuronal Ceroid Lipofuscinosis (ANCL) Caused by Mutations in Cysteine String Protein-Alpha (CSPalpha)
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Central Processing of Visual Information
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Central thalamic deep brain stimulation to regulate arousal and cognition
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Contribution of G Protein Coupled Estrogen Receptor to Changes in Hypothalamic Plasticity and Hypertension Susceptibility in Mice with Accelerated Ovarian Failure
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Defining the Effects of Astrocytic TDP-43 Dysregulation on Hippocampal Function
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Development of novel genomic approaches for profiling cellular temporal-spatial dynamics of neurogenesis in Aging and Alzheimer''s disease
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Dietary sodium, neurovascular dysfunction and cerebrovascular risk
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Dissecting STXBP1 dysfunction in a novel mouse model of STXBP1 Encephalopathies
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Dissecting immune resilience mechanism in human neuron-microglia chimera model
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Elucidate the Roles of Alzheimer''s Disease Variants in Gene Expression and AD Phenotypes
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Elucidating the Cell-Type Specific Neuroprotective Mechanisms in the APOE3 Christchurch Mutation in Alzheimer''s Disease
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Epilepsy Multiplatform Variant Prediction (EpiMVP)
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Essential roles of DAP12 in tau metabolism and inflammation in Alzheimer''s disease
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Ethnicity-Associated, Differential Cns Demyelinating Autoimmune Disease Severity: Reconciling Identity, Ancestry And Neurotoxic Antibody Response
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Evaluation of a novel human cGAS inhibitor using human iPSC derived models
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Exploring HIV-associated Neurocognitive Disorder (HAND) and HIV Latency at the Single Cell Level in Cerebral Organoids
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Exploring exosomes in neurodevelopmental and neuropsychiatric diseases using brain organoids
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Function of Fixational Instability During Natural Viewing
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GABAergic Interneuron Dysfunction in Developing Cortical Circuits Underlying Autism Spectrum Disorders
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Genetic and metabolic strategies for mutant CHCHD10 neuromuscular disorders
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Genetic circuitry governing heart growth and repair
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Genome-wide identification and characterization of Alzheimer''s Disease-associated enhancers
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Global mapping of altered neural circuits in a mouse model of DDX3X mutations
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Gut Immunity, Neurovascular dysregulation and Cognitive Impairment
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HEVOLUTION NETWORK ON SENESCENCE IN AGING
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Harboring the Initial Trigger of Multiple Sclerosis
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Hypertension, tau and neurodegeneration
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Identification and development of CD33 inhibitors and pre-RNA splicing modulators
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Immune Privilege, CNS Autoimmunity, and Clostridium perfringens Epsilon Toxin
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In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissues
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Insulin resistance and metabolic network remodeling in Alzheimer''s disease: a systems approach
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Integrative Single Cell Isoform And Chromatin Accessibility Mapping Of Chronic Opioid Exposure In Cognitive Brain Areas In HIV
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Integrative Single Cell isoform and chromatin accessibility Mapping of Chronic Opioid Exposure in Cognitive Brain Areas in HIV
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Investigating the Neurobiology of Early Cognitive Impairment
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Investigating the mechanistic contribution of Cav1.2 channels in extinction of cocaine-associated memories
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Investigating the role of cGAS signaling and microglial senscence in tauopathy
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Investigating the role of cGAS signaling and microglial senscence in tauopathy
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JSMF Covid-19 Consortium for Recovery of Consciousness
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Linking tau proteostasis with neuronal activity in FTD
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Maladaptive Antiviral Pathways In Alzheimer''S Disease
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Mechanisms of anosmia and brain infection in a mouse model of COVID-19
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Metabolic landscape and mitochondrial ROS balance in brain ischemia/reperfusion
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Metabolic origin of oxidative stress injury in brain ischemia/reperfusion
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Metabolic remodeling of skeletal muscle in mitochondrial myopathies
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Methods to optimize the benzofuran and benzothiophene human cGAS inhibitor leads
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Mitochondrial Complex III Free Radicals in Dementia-Related Proteinopathy and Neuroinflammation
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Mitochondrial Integrated Stress Response In Neurological Diseases
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Mitochondrial and Metabolic Dysfunction in Age-Related Neurodegeneration
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Mitochondrial proton leak and neonatal brain injury
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Model and identify genetic modifiers of PSP 4R tauopathies in human neurons
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Model human neuron-microglia interactions in chimera model of PSP and other 4R tauopathies
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Modeling pathological Tau propagation in human brain cells in vivo
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Molecular control of cardiac regenerative potential
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Molecular mechanisms and effects of Alzheimer''s-related lipid dysregulation
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Multiome measurements connecting transcription start sites at single-nucleotide resolution, DNA methylation and open chromatin status to splicing outcome across single cells in health and disease
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Neural Mechanism for the assembly of GABAergic in the cerebral cortex
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NeuroNex: From Odor to Action:Discovering Principles of Olfactory-Guided Natural Behavior
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Neurovascular and neuronal network dysfunction in tauopathy mouse models
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Pathogenic mechanisms and therapeutic strategies for CHCHD10 ALS
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Postdoctoral Fellowship Program in ALZHEIMER''S DISEASE Research
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Postnatal development of the cerebellar circuitry in the KIKO mouse model of Friedreich''s ataxia
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Rainwater Drug Discovery Grant
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Role of CaMKII-alpha ubiquitination in ischemic stroke
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Role of fixational eye movements and saccades in processing spatial information in V1-V2-V4 networks
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Role of perivascular macrophages in ApoE4-induced neurovascular dysfunction
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Role of prohibitin nitrosylation in its neuroprotective functions
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SRA
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Selective frataxin deficiency in glial cells in vivo in novel mouse models of Friedreich''s ataxia
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Stroke Impact (Stroke Immune Mediated Pathways and Cognitive Trajectory)
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Study of Selective Cell and System Vulnerability in Alzheimer''s Disease
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Synaptic vesicle changes in synucleinopathies
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Targeting maladaptive innate immune response to treat PD
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Tau proteostasis by chaperone-complexes in tauopathies including Alzheimer''s disease
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Tau-induced postsynaptic dysfunction in tauopathy models
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The Alzheimer''s Disease Tau Platform Clinical Trial
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The impact of beta- and gamma-synucleins on alpha-synuclein''s synaptic function
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The impact of synaptic vesicle-binding of alpha-synuclein on neuron function and neuropathology
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The role of FMN loss by mitochondrial Complex I in neonatal hypoxic-ischemic brain injury
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The role of VAMP2 in alpha-synuclein function and pathology
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The role of dendritic cells in regulating the gut-brain immune axis in ischemic stroke
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Uncovering Dementia-Related Lipid Alterations and Mechanisms in Astrocytes
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Uncovering the role of astrocyte RNA regulation in the central nervous system
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Understanding Genetic Complexity in Spina Bifida
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cGAS inhibitors for Alzheimer''s disease treatment
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tPA and cerebrovascular regulation in a model of ß-amyloid pathology