Medicine-Hematology and Medical Oncology
Academic Department
Faculty Research Areas
Affiliation
Research
administers grant
- 2021 Early Career Investigator''s Award
- 3D co-culture system to characterize and target leukemia stem cells
- A Phase Ib trial of tazemetostat plus mosuntezumab in untreated follicular lymphoma
- A Program for Metastatic Breast Cancer Research
- A bioengineered model of tumor vessel interactions in pancreatic cancer
- A novel, short isoform of the +TIP microtubule (MT) binding protein CLIP170 confers taxane resistance by obstructing the MT pore.
- AIDS Malignancy Consortium (AMC)
- ASH transfer
- ATHNdataset Hereditary Antithrombin Deficiency (HAD) Pilot Project
- Addgene 796255
- Alternatively spliced cell surface proteins as drivers of leukemogenesis and targets for immunotherapy
- American-Italian Cancer Foundation (AICF) Post-Doctoral Research Fellowship
- Autoimmune Stem-like CD8 T cells in Type I Diabetes
- Automated Rapid Dual-Extraction of DNA and RNA from Single Cells in Microplates
- BRIDGE (Blood cancer Research Initiative Developing Greater Engagement) with Community Patients
- BioPharma Alliance Agreement- Janssen Research & Development
- Biophysical roles of pre-metatstatic niche evolution on transport of circulating tumor cells
- Cardiovascular Risk of Antiretroviral Therapy Drugs in HIV
- Characteristics and Outcomes of Patients with Diffuse Large B-Cell Lymphoma (DLBCL) Receiving Frontline Treatment at Cancer Centers Within the LEO Cohort
- Characterization of the genomic and transcriptional landscape and role of tumor immune environment in multiple myeloma with extramedullary disease
- Characterizing the role of BCL10 somatic mutations in B cell lymphomas
- Clonal Hematopoiesis as a determinant for bone marrow toxicities for targeted radiation therapies in prostate cancer.
- Core: Targeting Enhancer Dysfunction in Hematological Malignancy- Core B
- Define genetically/epigenetically modified targets in the immune niche of DLBCLs- Project 2
- Defining The Functional Impact Of Composite Mutations In Oncogene-Driven Urothelial Cancer Using Circulating-Tumor Dna And Single-Cell Sequencing
- Defining the epigenetic landscape and therapeutic vulnerabilities of Richter''s syndrome in CRISPR-based mouse models
- Defining the impact of Kras heterogeneity on the tumor microenvironment
- Defining the impact of Kras mutational heterogeneity on the tumor microenvironment in pancreatic cancer
- Determinants Of The Racial/Ethnic Disparity In MGUS Risk: An Epidemiologic Study In 4 Cohorts
- Development of a platform for high throughput drug screening on CTC-derived organoid in breast and colorectal cancer
- Directing Fate, Subtype Identity And Survival In Human Pluripotent-Derived Midbrain Dopamine Neurons
- Discovery and therapeutic targeting of novel mechanisms driving Double Hit Lymphomas
- Dysregulated mechanoimmunology of epigenetics-driven lymphomas
- Early intervention for the prevention of blood cancer development.
- Elucidating Metabolic Pathways Regulating Germinal Center B Cells And Derived Lymphomas
- Elucidating the role of follicular dendritic cells in EZH2-mutated follicular lymphoma
- Elucidating the role of follicular dendritic cells in EZH2-mutated follicular lymphoma progression and transformation - Caitlin Gribbin
- Enhancing the Efficacy of Docetaxel in Prostate Cancer
- Epigenetic basis and therapeutic interdiction of FL progression
- Exploiting tumor metabolism to optimize T cell therapy
- Exploring the roles of EZH2 mutation for the development of double hit lymphoma and acquisition of chemotherapy resistance
- Heating cold prostate tumors with PSMA-targeted alpha therapy and pembrolizumab
- Hereditary Antithrombin Deficiency and Pregnancy
- Identifying B cell developmental changes and therapeutic vulnerabilities of MGA-mutant Richter''s syndrome
- Immune Tolerance Network
- Immunogenomic determinants of ethnic disparities in clinical outcomes for urothelial cancer patients
- Immunologic Eradication of Myeloproliferative Neoplasm Stem Cells
- Immunomodulatory Ligand B7-1 Targets p75 Neurotrophin Receptor in Neurodegeneration
- Inhibiting EZH2 to Improve Immunotherapies in B-Cell Lymphomas
- Inhibiting EZH2 to improve CAR T immunotherapy in B-cell lymphomas
- Investigating the non-cell autonomous immune effects of mutant p53 in pancreatic cancer
- Investigating the tumor metabolism-hypoxia-vasculature axis in the response of TNBC to immunotherapy
- Janssen Biopharma Agreement
- Lymph node-targeted multistage chemoimmunotherapy for lymphoma
- Lymphoid Experimental Therapeutics Platform to Study Cooperative Signaling in Human Lymphomas
- Metabolic and Inflammatory Response to a Whole Food Plant-Based Diet in Overweight/Obese Men with Prostate Cancer Receiving Androgen Deprivation Therapy: A Phase II Randomized Study
- Molecular Mechanisms of eIF4E mediated transformation
- Molecular regulation and expression of Trop-2 in advanced prostate cancer: Identifying optimal therapeutic niches
- Mutational and Aging Risk Factors for Myelodysplastic Syndrome
- NRG Oncology Network Group Operations Center
- New Approaches to Breast Cancer Prevention
- Novel Approach to Improving Prostate Cancer Screening Among African American Men
- Oncogenic Impact of eIF4E-dependent RNA export in cancer
- Optimization Of Urinary DNA Deep Sequencing Tests To Enhance Clinical Staging Of Bladder Cancer Patients
- Pre-malignant mutation landscape and risk factors for progression to hematologic cancers
- Precision epigenetic therapy for SETD2+/- B cell lymphomas
- Precision translation of therapeutic regimens for follicular lymphoma
- Preventing follicular lymphoma progression and transformation through precision therapy
- Preventing follicular lymphoma progression and transformation through precision therapy
- Restoring lymphoma immunosurveillance by combined EZH2 inhibition and immunotherapy.
- Role of BCL10 somatic mutations in lymphomagenesis and response to BCR-targeted therapies
- Role of Chromatin Remodeling Complex BAF in Immunity and Lymphoma
- Role of chromatin remodeling complex BAF in immunity and lymphoma
- Role of the stromal microenvironment in B-cell lymphoma progression and immune escape
- Role of the stromal microenvironment in B-cell lymphoma progression and immune escape
- SETD2 and H1 Project
- SRA with BMS
- TOX-driven CD8 T cell differentiation and dysfunction in tumors - R01CA269733. (PA-20-185)
- Targeted Small Molecule Inhibitors for Inv(16) Leukemia
- Targeted Therapies
- Targeting APOBEC3A-induced chromosomal instability as a driver of metastasis in bladder cancer
- Targeting APOBEC3A-induced genetic heterogeneity and drug resistance in bladder cancer
- Targeting Enhancer Dysfunction in Hematological Malignancy- Project 5
- Targeting Epigenetic Circuits in B-Cell Lymphomas
- Targeting MALT1 to Enhance Anti-Lymphoma Immunity and Response to Immunotherapy
- Targeting MPN and Progenitor Cells
- Targeting Unmet Needs For B-cell Lymphomas
- Targeting cytidine deaminase-induced chromosomal instability as a driver of metastasis in bladder cancer
- Targeting immune escape in Cluster 5 DLBCL
- The Lymphoma Epidemiology of Outcomes (LEO)
- The Lymphoma Epidemiology of Outcomes (LEO) Cohort Study
- The National Cord Blood Network, National Chair
- The National Cord Blood Network, Participating Center
- The Ohio State University as a Lead Academic Organization (LAO) for the Experimental Therapeutics Clinical Trials Network
- The Role of SPEN as Tumor Suppressor in BN2 DLBCL
- The association of HER2 expression on circulating tumor cells with the response to cyclin-dependent kinase 4/6 inhibitors in hormone receptor positive, HER2 negative metastatic breast cancer
- The impact of changes in chromatin architecture on cancer phenotypes and tumor progression
- The role of SPEN and NOTCH2 mutations in pathogenesis of DLBCL.
- Therapeutic Targeting of AR Variant Prostate Cancer with a Novel Antibody Drug Conjugate
- Therapeutic targeting of SIRT3 for aggressive and refractory lymphomas
- Tissue-Engineered Models of Lymphatic Drainage in Breast Cancer
- Tracking MPN Fitness to speed development of disease modifying agents for MPNs
- Tumor-metabolism-driven therapies to overcome TNBC immune resistance
- Understanding resistance mechanisms to protein arginine methyltransransferase Inhibitors in Lymphoma
- Understanding the in vivo impact of immunotherapies in splenic lymphoma by intravital three-photon microscopy
- Utilizing EZH2 Inhibition to Improve Immune Therapies in Follicular Lymphoma