Manipulation of single molecules in biology. Review uri icon

Overview

abstract

  • The mechanical manipulation of single biological molecules is stimulating new and exciting research in many fields of study, including molecular motor mechanics, biopolymer properties, protein unfolding, receptor-ligand interactions, and more. Some recent highlights include the elucidation of the coupling ratios of myosin and kinesin, the demonstration of oscillatory forces in dynein arms, the determination of the force-velocity relation of RNA polymerase, and the direct mechanical observation of unfolding of single domains of titin and tenascin.

publication date

  • February 1, 1999

Research

keywords

  • Biopolymers
  • Molecular Biology
  • Molecular Motor Proteins
  • Protein Folding

Identity

Scopus Document Identifier

  • 0032929393

PubMed ID

  • 10047511

Additional Document Info

volume

  • 10

issue

  • 1