Evaluation of left ventricular wall motion, volumes, and ejection fraction by gated myocardial tomography with technetium 99m-labeled tetrofosmin: a comparison with cine magnetic resonance imaging. Academic Article uri icon

Overview

abstract

  • BACKGROUND: Whether left ventricular function can be assessed accurately by gated single photon emission computed tomography (SPECT) in patients with myocardial infarction and severe perfusion defects is not well known. METHODS AND RESULTS: Twenty-five patients with an acute myocardial infarction underwent 99mTc-labeled tetrofosmin (99mTc-tetrofosmin) gated SPECT and cine magnetic resonance imaging (MRI). Wall motion was assessed in 13 left ventricular segments using a 5-point scoring system ranging from 3 (normal) to -1 (dyskinetic). Exact agreement for wall motion scores between gated SPECT and MRI was excellent (92%, kappa = 0.82). Furthermore, correlations between the two techniques were also good for end-diastolic volume (r = 0.81, P < .0001), end-systolic volume (r = 0.92, P < .0001), and ejection fraction (r = 0.93, P < .0001). CONCLUSION: In patients with a recent myocardial infarction, 99mTc-tetrofosmin gated SPECT provides reliable evaluation of global and regional ventricular function and volumes.

publication date

  • January 1, 1999

Research

keywords

  • Magnetic Resonance Imaging, Cine
  • Myocardial Infarction
  • Organophosphorus Compounds
  • Organotechnetium Compounds
  • Radiopharmaceuticals
  • Tomography, Emission-Computed, Single-Photon
  • Ventricular Function, Left

Identity

Scopus Document Identifier

  • 0033034954

PubMed ID

  • 10070835

Additional Document Info

volume

  • 6

issue

  • 1 Pt 1