Cloning, tissue-specific expression, gene structure and chromosomal localization of human phosphatidylcholine transfer protein. Academic Article uri icon

Overview

abstract

  • Phosphatidylcholine transfer protein (PC-TP) is a cytosolic protein that catalyzes intermembrane transfer of phosphatidylcholines in vitro. We have cloned a cDNA encoding the human ortholog of PC-TP and have determined its tissue-specific expression as well as genomic organization. Radiation hybrid mapping localized the human gene, PCTP, to chromosome 17q21-22 and PCR-based single strand conformation polymorphism analysis of an interspecific backcross assigned mouse Pctp to the region of syntenic conservation on chromosome 11.

publication date

  • October 28, 1999

Research

keywords

  • Androgen-Binding Protein
  • Carrier Proteins
  • Chromosomes, Human, Pair 17

Identity

Scopus Document Identifier

  • 0032748021

PubMed ID

  • 10542325

Additional Document Info

volume

  • 1447

issue

  • 2-3