Uncommon metastasis of a glioblastoma multiforme in liver and spleen. Academic Article uri icon



  • A case of a glioblastoma multiforme is presented. Craniotomy was performed with total resection of the right temporal tumor. Postoperatively, the patient received adjuvant radiotherapy, but 6 months after therapy he developed severe nausea and weight loss. Recurrence of an intracranial tumor in the right temporal region with nodules in the liver and spleen were detected by CT scan. Fine-needle biopsies of the liver confirmed the diagnosis of a glioblastoma metastasis with characteristic immunohistochemical staining for glial fibrillary acidic protein. This rare case of an intracerebral glioblastoma metastasizing to liver and spleen was managed by systemic chemotherapy.

publication date

  • January 1, 2000



  • Brain Neoplasms
  • Glioblastoma
  • Liver Neoplasms
  • Splenic Neoplasms


Scopus Document Identifier

  • 0034085901

PubMed ID

  • 10773729

Additional Document Info


  • 61


  • 3