Acidic fibroblast growth factor is expressed sequentially in the progression from Barrett's esophagus to esophageal adenocarcinoma. Academic Article uri icon

Overview

abstract

  • Acidic fibroblast growth factor 1 (FGF-1) is sequentially accumulated in Barrett's esophagus and its expression in glandular dysplasias is independent of esophageal adenocarcinoma. This suggests that FGF-1 immunohistochemistry could be used as an adjunct to the routine histopathologic diagnosis of dysplasia in Barrett's esophagus. The data also underscore the important role of fibroblast growth factors in tumorigenesis.

publication date

  • January 1, 2001

Research

keywords

  • Adenocarcinoma
  • Barrett Esophagus
  • Esophageal Neoplasms
  • Esophagus
  • Fibroblast Growth Factor 1

Identity

Scopus Document Identifier

  • 0034928392

PubMed ID

  • 11422301

Additional Document Info

volume

  • 14

issue

  • 1