Phosphorylation of component a of the human erythrocyte membrane in myotonic muscular dystrophy. Academic Article uri icon

Overview

abstract

  • Endogenous membrane protein kinase activity in fresh erythrocyte ghosts is altered in myotonic muscular dystrophy. Phosphorylation of erythrocyte Component a, which migrates with an apparent molecular weight of 90,000 to 100,000, is significantly reduced compared to age- and sex-matched controls. The difference in endogenous membrane protein kinase activity in fresh RBC membranes lends confirmation to the suggestion that myotonic dystrophy is a disease of widespread membrane alterations.

publication date

  • January 1, 1975

Research

keywords

  • Blood Proteins
  • Erythrocytes
  • Muscular Dystrophies
  • Protein Kinases

Identity

Scopus Document Identifier

  • 0016658479

PubMed ID

  • 123592

Additional Document Info

volume

  • 20

issue

  • 1-2