Liquid-based vs. conventional smears in fine needle aspiration of bone and soft tissue tumors. Academic Article uri icon

Overview

abstract

  • OBJECTIVE: To compare the accuracy of fine needle aspiration cytology of bone and soft tissue tumors utilizing ThinPrep (TP) (Cytyc Corporation, Boxborough, Massachusetts, U.S.A.) vs. conventional smears (CS). STUDY DESIGN: Fine needle aspiration cytology from bone and soft tissue tumors was processed and assessed for cellularity, nuclear and cytoplasmic preservation, cellular architecture and stromal background with both the TP liquid-based smear technique and conventional methods. RESULTS: An accurate diagnosis was made in 13% of TP cases as compared to 64% in CS cases. CONCLUSION: CS of fine needle aspiration sample is far superior to TP in diagnosing tumors of bone and soft tissues. Preservation of cytoplasmic features and cellular architecture was superior in conventionally prepared smears.

publication date

  • March 1, 2003

Research

keywords

  • Biopsy, Needle
  • Bone Neoplasms
  • Cytological Techniques
  • Microtomy
  • Soft Tissue Neoplasms

Identity

PubMed ID

  • 12685189

Additional Document Info

volume

  • 47

issue

  • 2