CSF hypocretin levels in Guillain-Barré syndrome and other inflammatory neuropathies. Academic Article uri icon

Overview

abstract

  • CSF hypocretin-1 was measured in 28 Guillain-Barré syndrome (GBS), 12 Miller-Fisher syndrome, 12 chronic inflammatory demyelinating polyneuropathy (CIDP), and 48 control subjects. Seven GBS subjects had undetectably low hypocretin-1 levels (<100 pg/mL). Hypocretin-1 levels were moderately reduced in an additional 11 GBS, 5 Miller-Fisher syndrome, and 1 CIDP subject. Low levels in GBS occurred early in the disease and were associated with upper CNS level abnormalities.

publication date

  • September 23, 2003

Research

keywords

  • Carrier Proteins
  • Guillain-Barre Syndrome
  • Intracellular Signaling Peptides and Proteins
  • Miller Fisher Syndrome
  • Neuropeptides
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Identity

Scopus Document Identifier

  • 10744229433

PubMed ID

  • 14504329

Additional Document Info

volume

  • 61

issue

  • 6