Adjuvant therapy following resection for pancreatic adenocarcinoma. Review uri icon

Overview

abstract

  • Pancreatic adenocarcinoma remains a lethal disease. Approximately 10% to 15% of patients who are able to undergo resection will be alive at 5 years, but most of those will have late recurrence and ultimately die of the disease. Multiple adjuvant treatments have been tested, including extended operations, chemotherapy, radiation therapy, and immunotherapy--the vast majority with minimal, if any, effect. There is a small suggested benefit from adjuvant chemotherapy but little other cause for optimism. At the current time, given the relative failure of standard adjuvant approaches, it is reasonable to suggest that all patients should have tissue harvested for molecular markers and enter into investigative regimens.

publication date

  • October 1, 2004

Research

keywords

  • Adenocarcinoma
  • Antineoplastic Combined Chemotherapy Protocols
  • Pancreatic Neoplasms

Identity

Scopus Document Identifier

  • 4444351076

PubMed ID

  • 15350934

Additional Document Info

volume

  • 13

issue

  • 4