Cognitive effects of cytotoxic cancer chemotherapy: predisposing risk factors and potential treatments. Review uri icon

Overview

abstract

  • Increasing evidence suggests that systemic cancer chemotherapy can have significant long-term effects on cognition, particularly on verbal learning, memory, attention, and speed of information processing. These deficits can be a source of significant distress to survivors. There is much less known about the mechanisms, predisposing vulnerabilities, and treatment of these deficits. We will summarize current knowledge of chemotherapy-associated cognitive deficits. Emerging theories about the role of selected genetic polymorphisms in heightening the vulnerability to chemotherapy-induced cognitive decline will be described.

publication date

  • October 1, 2004

Research

keywords

  • Antineoplastic Combined Chemotherapy Protocols
  • Cognition Disorders

Identity

PubMed ID

  • 15355759

Additional Document Info

volume

  • 6

issue

  • 5