Myelodysplasia with isolated trisomy 15: a 15-year follow-up without specific therapy. uri icon

Overview

abstract

  • A 41-year-old patient manifested pancytopenia with macrocytosis following pesticide exposure. She was later found to have myelodysplasia with trisomy 15. Over a 15-year period of observation, and with no specific therapy, her hematological disorder remains stable, despite persistence of the chromosomal aberration. This and similar reported observations suggest that the course of this uncommon form of myelodysplasia is often indolent and not accurately predicted by application of the widely used International Prognostic Scoring System for the myelodysplastic syndromes.

publication date

  • March 1, 2006

Research

keywords

  • Chromosomes, Human, Pair 15
  • Myelodysplastic Syndromes
  • Trisomy

Identity

Scopus Document Identifier

  • 33645105649

Digital Object Identifier (DOI)

  • 10.1097/00000441-200603000-00009

PubMed ID

  • 16538078

Additional Document Info

volume

  • 331

issue

  • 3