Surgery for colorectal and sarcomatous pulmonary metastases: history, current management, and future directions.

Overview

This article provides a historical review of metastasectomy, reviews current surgical management approaches, and proposes what direction future research must take to determine whether there is a survival advantage associated with pulmonary metastasectomy and how best to integrate metastasectomy with medical therapies, primarily induction, and adjuvant chemotherapy.