Tissue engineering and rotator cuff tendon healing. Academic Article uri icon

Overview

abstract

  • Rotator cuff tears are common soft-tissue injuries that often require surgical treatment. Initial efforts to better tendon healing centered on improving the strength of the repair. More recent studies have focused on biologic enhancement of the healing process. Tissue engineering is a multidisciplinary field that involves the application of scientific principles toward creating living tissue to replace, repair, or augment diseased tissue. Gene therapy involves the transfer of a certain gene into a cell so that the cell translates the gene into a specific protein. The advantage of using a gene-therapy, tissue-engineered approach to effect healing rests in the ability of the physician to select growth factors with documented roles in the tendon-healing cascade. Ideally, an improvement to the current repair technique would yield improved tendon healing leading to improved clinical results.

publication date

  • May 23, 2007

Research

keywords

  • Rotator Cuff
  • Tendon Injuries
  • Tissue Engineering
  • Wound Healing

Identity

Scopus Document Identifier

  • 34548606996

Digital Object Identifier (DOI)

  • 10.1016/j.jse.2007.03.004

PubMed ID

  • 17524676

Additional Document Info

volume

  • 16

issue

  • 5 Suppl