Depression and IL-6 blood plasma concentrations in advanced cancer patients. Academic Article uri icon

Overview

abstract

  • The authors explored the relationship between depression and interleukin-6 (IL-6) blood plasma concentrations among advanced-stage cancer patients. Seventy-three patients with advanced cancer were rated on depression with the Hamilton Rating Scale for Depression and gave blood to be assayed for blood plasma concentration of IL-6. Initial results found no correlation between depression and IL-6. Subsequent analyses found that among those whose blood was drawn within 48 hours of interview completion, depression and IL-6 were highly correlated. Future studies focusing on the relationship between immune functioning and depression must be particularly vigilant regarding methodological issues.

publication date

  • January 1, 2008

Research

keywords

  • Depressive Disorder
  • Interleukin-6
  • Neoplasms

Identity

Scopus Document Identifier

  • 37549071485

Digital Object Identifier (DOI)

  • 10.1176/appi.psy.49.1.64

PubMed ID

  • 18212178

Additional Document Info

volume

  • 49

issue

  • 1