Published international classification of retinoblastoma (ICRB) definitions contain inconsistencies--an analysis of impact.
Academic Article
Overview
abstract
PURPOSE: To determine the impact of subtle differences (most notably in their classification of group E eyes) in two published versions of the ICRB (Philadelphia and the Children's Hospital Los Angeles). METHODS: Analysis of a series of 96 eyes with intra-ocular retinoblastoma. RESULTS: The disparate criteria of the 2 published ICRB schemas affected group assignment of 5.2% of the eyes (25% of the group E eyes). CONCLUSION: Discrepancies need to be reconciled to ensure accurate and uniform application of the ICRB.