A prospective observational study examining quality of life in patients with malignant gastric outlet obstruction. Academic Article uri icon

Overview

abstract

  • BACKGROUND: Gastric outlet obstruction (GOO) often complicates advanced malignancy. Palliative options include surgical bypass, endoscopic stent, percutaneous gastrostomy (PEG), or percutaneous jejunostomy (PEJ). METHODS: We enrolled 50 patients with GOO secondary to unresectable primary or metastatic cancer in a study examining palliative interventions. Validated instruments assessed quality of life (QOL) at baseline, 1 month, and 3 months following intervention. RESULTS: Median overall survival was 64 days. A shorter hospital stay and trend to lower mortality were observed after stent placement; solid food intake and rates of secondary intervention were comparable. Both stent and surgical bypass were associated with acceptable QOL outcomes. Fifteen patients refused participation at 1 month and 28 died of disease before 3 months, so 10 patients completed all surveys. CONCLUSIONS: Although malignant GOO is associated with poor survival, there are reasonable alternatives for palliation. QOL studies are difficult to complete in this population due to severity of illness and short life expectancy.

publication date

  • May 31, 2009

Research

keywords

  • Gastric Outlet Obstruction
  • Gastrointestinal Neoplasms
  • Quality of Life

Identity

Scopus Document Identifier

  • 67649622967

Digital Object Identifier (DOI)

  • 10.1016/j.amjsurg.2008.09.030

PubMed ID

  • 19482259

Additional Document Info

volume

  • 198

issue

  • 1