Collagenous fibroma (desmoplastic fibroblastoma) with a new translocation involving 11q12: a case report. uri icon

Overview

abstract

  • Collagenous fibroma (or desmoplastic fibroblastoma) is a rare, benign tumor usually centered in the subcutaneous tissue composed of spindle-shaped to stellate fibroblasts and myofibroblasts in a densely collagenous background. Three previous case reports have described a t(2;11)(q31;q12) in this entity. Herein, we report a case of collagenous fibroma of deep soft tissue with t(11;17)(q12;p11.2). The breakpoint at chromosome 11q12 appears to be pathogenetic in this rare neoplasm.

publication date

  • July 15, 2009

Research

keywords

  • Chromosomes, Human, Pair 11
  • Collagen
  • Fibroma
  • Soft Tissue Neoplasms
  • Translocation, Genetic

Identity

Scopus Document Identifier

  • 67649823763

Digital Object Identifier (DOI)

  • 10.1016/j.cancergencyto.2009.03.012

PubMed ID

  • 19596257

Additional Document Info

volume

  • 192

issue

  • 2