Female sexual dysfunction (FSD) encompasses a group of highly prevalent disorders characterized by problems related to sexual desire, arousal, orgasm, or pain. Among these is hypoactive sexual desire disorder (HSDD), a condition that causes marked distress and interpersonal difficulties. In view of the complexity of factors contributing to the various types of FSD, the identification of HSDD requires that it be carefully differentiated from other forms of sexual dysfunction. An understanding of the definitions of FSD and HSDD, their prevalence in various subpopulations of women, and their impact on quality of life can increase awareness of the importance of these disorders. Such knowledge will also help family physicians appreciate the place of HSDD within the spectrum of FSD and become better equipped to recognize this disorder in clinical practice.