It takes two to tango to the melanosome. Article uri icon

Overview

abstract

  • The role of clathrin adaptor proteins in sorting cargo in the biosynthetic and recycling routes is an area of intense research. In this issue, Delevoye et al. (2009. J. Cell Biol. doi:10.1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is essential for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes and for organelle biogenesis.

publication date

  • October 19, 2009

Research

keywords

  • Adaptor Protein Complex 1
  • Endosomes
  • Kinesin
  • Kinesins
  • Melanosomes

Identity

PubMed Central ID

  • PMC2768836

Scopus Document Identifier

  • 70449709871

Digital Object Identifier (DOI)

  • 10.1083/jcb.200909100

PubMed ID

  • 19841135

Additional Document Info

volume

  • 187

issue

  • 2