Neoadjuvant therapy of locally advanced gastric cancer. Review uri icon

Overview

abstract

  • Treatment of gastric cancer has evolved with the advent of randomized trials demonstrating chemotherapeutic agents with efficacy in advanced disease. Level I evidence supports delivering chemotherapy in the neoadjuvant setting; the data shows improvement in progression-free and overall survival. A clinical response to therapy is associated with improved R0 resection rates, pathologic response, and outcome in patients with locally advanced disease. Early assessment of metabolic response to therapy can potentially be utilized to tailor treatment.

publication date

  • March 15, 2010

Research

keywords

  • Stomach Neoplasms

Identity

Scopus Document Identifier

  • 77749240282

Digital Object Identifier (DOI)

  • 10.1002/jso.21483

PubMed ID

  • 20187070

Additional Document Info

volume

  • 101

issue

  • 4