Sphenoid masses in children: radiologic differential diagnosis with pathologic correlation. Review uri icon

Overview

abstract

  • Childhood central skull base masses are rare, often difficult to diagnose, and have overlapping imaging findings. In this review, we provide an overview of the epidemiology, clinical findings, and management of pediatric sphenoid bone and sphenoid sinus masses with an emphasis on imaging findings that may help to differentiate lesions. Radiologic-pathologic correlation is provided. Finally, an imaging-based algorithm is presented as a guide to help radiologists narrow their differential diagnoses. Some of the entities discussed are virtually unique to the pediatric population; others occur rarely in this age group but should be considered in the appropriate clinical setting. Entities included in the discussion are grouped into 2 categories: those that cause nonaggressive osseous remodeling and those that are more commonly associated with aggressive bone changes. Mucocele, aneurysmal bone cyst, giant cell lesions, meningioma, and fibrous dysplasia tend to remodel bone, while entities such as chordoma, craniopharyngioma, rhabdomyosarcoma, sinonasal carcinoma, and neuroblastoma may cause more aggressive local bone changes.

publication date

  • July 1, 2010

Research

keywords

  • Bone Diseases
  • Skull Base Neoplasms
  • Sphenoid Bone

Identity

PubMed Central ID

  • PMC7965862

Scopus Document Identifier

  • 79954528251

Digital Object Identifier (DOI)

  • 10.3174/ajnr.A2144

PubMed ID

  • 20595365

Additional Document Info

volume

  • 32

issue

  • 4