Inherited predisposition to cancer: introduction and overview. Review uri icon

Overview

abstract

  • The past three decades have witnessed an explosion in information regarding the genetic mutations underlying predisposition to common malignancies. Discoveries are now being made regarding genomic variants associated with disease risk for, and outcome following, treatment for cancer. Responsible translation of these discoveries to medical practice requires attention to principles of clinical utility as well as social and ethical aspects.

publication date

  • October 1, 2010

Research

keywords

  • Genetic Predisposition to Disease
  • Neoplastic Syndromes, Hereditary

Identity

Scopus Document Identifier

  • 77956305912

Digital Object Identifier (DOI)

  • 10.1016/j.hoc.2010.06.005

PubMed ID

  • 20816574

Additional Document Info

volume

  • 24

issue

  • 5