Immunotherapy for ovarian cancer: what's next? Review uri icon

Overview

abstract

  • In the past decade, we have witnessed important gains in the treatment of ovarian cancer; however, additional advances are required to reduce mortality. With compelling evidence that ovarian cancers are immunogenic tumors, immunotherapy should be further pursued and optimized. The dramatic advances in laboratory and clinical procedures in cellular immunotherapy, along with the development of powerful immunomodulatory antibodies, create new opportunities in ovarian cancer therapeutics. Herein, we review current progress and future prospects in vaccine and adoptive T-cell therapy development as well as immunomodulatory therapy tools available for immediate clinical testing.

publication date

  • November 15, 2010

Research

keywords

  • Cancer Vaccines
  • Immunotherapy
  • Ovarian Neoplasms

Identity

PubMed Central ID

  • PMC3068064

Scopus Document Identifier

  • 79952296527

Digital Object Identifier (DOI)

  • 10.1200/JCO.2009.27.2369

PubMed ID

  • 21079136

Additional Document Info

volume

  • 29

issue

  • 7